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negative regulation of G-protein coupled receptor internalization

Known as: down regulation of G-protein coupled receptor internalization, down-regulation of G-protein coupled receptor internalization, downregulation of G-protein coupled receptor internalization 
Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor internalization. [GO_REF:0000058, GOC… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Selective Cytotoxicity to HER2 Positive Breast Cancer Cells by Saporin-Loaded Nanobody-Targeted Polymeric Nanoparticles in Combination with Photochemical Internalization
In cancer treatment, polymeric nanoparticles (NPs) can serve as a vehicle for the delivery of cytotoxic proteins that have… Expand
2013
2013
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties.
CD133 is a putative cancer stem cell (CSC) marker for a number of different cancers and is suggested to be a therapeutic target… Expand
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Highly Cited
2010
Highly Cited
2010
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization.
Small interfering RNAs (siRNAs) show potential for the treatment of a wide variety of pathologies with a known genetic origin… Expand
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2010
2010
Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing.
In this study, we have investigated the possibility of combining a cyclodextrin-containing polymer (CDP) with siRNA molecules to… Expand
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2010
2010
Light-induced gene expression using messenger RNA molecules.
The exploration of messenger RNA (mRNA) as a potential therapeutic regulator of gene expression has been significantly reduced by… Expand
2008
2008
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes.
Photochemical internalization (PCI) is a physico-chemical targeting method that enables light directed delivery of nucleic acids… Expand
Highly Cited
2007
Highly Cited
2007
Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy.
  • P. Lai, P. Lou, +5 authors M. Shieh
  • Journal of controlled release : official journal…
  • 2007
    • Corpus ID: 27128580
Coupling anticancer drugs to synthetic polymers is a promising approach to improve the efficacy and reduce the side effects of… Expand
Highly Cited
2007
Highly Cited
2007
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.
Photochemical internalization (PCI) is a novel technology of macromolecular delivery. By PCI, endocytosed membrane-impermeable… Expand
Highly Cited
2007
Highly Cited
2007
Photochemical internalization enhances silencing of epidermal growth factor receptor through improved endosomal escape of siRNA.
Photochemical internalization (PCI) has been employed as a tool for site-specific intracellular delivery of a variety of… Expand
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2007
2007
Cytosolic Delivery of Liposomally Targeted Proteins Induced by Photochemical Internalization
PurposeThe application of therapeutic proteins is often hampered by limited cell entrance and lysosomal degradation, as… Expand
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