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negative regulation of G-protein coupled receptor internalization

Known as: down regulation of G-protein coupled receptor internalization, down-regulation of G-protein coupled receptor internalization, downregulation of G-protein coupled receptor internalization 
Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor internalization. [GO_REF:0000058, GOC… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Selective Cytotoxicity to HER2 Positive Breast Cancer Cells by Saporin-Loaded Nanobody-Targeted Polymeric Nanoparticles in Combination with Photochemical Internalization
In cancer treatment, polymeric nanoparticles (NPs) can serve as a vehicle for the delivery of cytotoxic proteins that have… Expand
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2013
2013
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties.
CD133 is a putative cancer stem cell (CSC) marker for a number of different cancers and is suggested to be a therapeutic target… Expand
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2010
2010
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization.
Small interfering RNAs (siRNAs) show potential for the treatment of a wide variety of pathologies with a known genetic origin… Expand
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2010
2010
Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing.
In this study, we have investigated the possibility of combining a cyclodextrin-containing polymer (CDP) with siRNA molecules to… Expand
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2010
2010
Light-induced gene expression using messenger RNA molecules.
The exploration of messenger RNA (mRNA) as a potential therapeutic regulator of gene expression has been significantly reduced by… Expand
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2008
2008
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes.
Photochemical internalization (PCI) is a physico-chemical targeting method that enables light directed delivery of nucleic acids… Expand
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Highly Cited
2007
Highly Cited
2007
Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy.
Coupling anticancer drugs to synthetic polymers is a promising approach to improve the efficacy and reduce the side effects of… Expand
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Highly Cited
2007
Highly Cited
2007
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.
Photochemical internalization (PCI) is a novel technology of macromolecular delivery. By PCI, endocytosed membrane-impermeable… Expand
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2007
2007
Cytosolic Delivery of Liposomally Targeted Proteins Induced by Photochemical Internalization
PurposeThe application of therapeutic proteins is often hampered by limited cell entrance and lysosomal degradation, as… Expand
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Highly Cited
2007
Highly Cited
2007
Photochemical internalization enhances silencing of epidermal growth factor receptor through improved endosomal escape of siRNA.
Photochemical internalization (PCI) has been employed as a tool for site-specific intracellular delivery of a variety of… Expand
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