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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

TLDR
The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities, and a checklist is provided with summaries of key points.
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Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

TLDR
Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles that aims to provide a single authoritative source for information on vesicle structure and function.
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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle.

TLDR
The results suggest achievement of two levels of targeting: tumor tissue selective delivery via the nanoparticle ligand and gene pathway selectivity via the siRNA oligonucleotide, opening the door for better targeted therapeutics with both tissue and gene selectivity, also to improve targeted therapies with less than ideal therapeutic targets.
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Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

TLDR
The data show that hypoxia and endothelial activation are reflected in RNA and protein exosome composition, and that exposure to high sugar concentrations alters exosomes protein composition only to a minor extend, and does not affectExosome RNA composition.
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In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

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Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper

TLDR
This position paper was written by the participants of the workshop to give an overview of the current state of knowledge in the field and to clarify that incomplete knowledge – of the nature of EV(-RNA)s and of how to effectively and reliably study them – currently prohibits the implementation of gold standards in EV-RNA research.
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Exosome mimetics: a novel class of drug delivery systems

TLDR
Insight is provided into the composition and functional properties of exosomes, and components which could be used to enhance the drug delivery properties of Exosome mimetics are focused on.
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Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment.

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EVpedia: a community web portal for extracellular vesicles research

TLDR
An improved version of EVpedia, a public database for EVs research, is presented, which contains a database of publications and vesicular components, identification of orthologous vesicle components, bioinformatic tools and a personalized function.
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Extracellular vesicles for drug delivery.

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