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lapatinib

Known as: N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine, N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine, lapatinib [Chemical/Ingredient] 
A synthetic, orally-active quinazoline with potential antineoplastic properties. Lapatinib reversibly blocks phosphorylation of the epidermal growth… 
National Institutes of Health

Papers overview

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2011
2011
The development of the multilevel fast multipole algorithm (MLFMA) and its multiscale variants have enabled the use of integral… 
2010
2010
In most of the existing probability hypothesis density (PHD) filters, the clutter is modeled as a Poisson random finite set (RFS… 
Highly Cited
2009
Highly Cited
2009
Prior studies demonstrated that resistance to the ERBB1/2 inhibitor Lapatinib in HCT116 cells was mediated by increased MCL-1… 
Highly Cited
2009
Highly Cited
2009
Abstract—Based on message passing interface (MPI) of the PC Clusters, the parallel method of moment (MOM) is applied to the… 
Highly Cited
2009
Highly Cited
2009
PURPOSE This study (EGF100262) sought to establish the recommended phase II dose of lapatinib with chemoradiotherapy in patients… 
2009
2009
In order to more exactly predict femtosecond pulse laser induced damage threshold, an accurate theoretical model taking into… 
Highly Cited
2008
Highly Cited
2008
We have defined some of the mechanisms by which the kinase inhibitor lapatinib kills HCT116 cells. Lapatinib inhibited radiation… 
Highly Cited
2002
Highly Cited
2002
The present study deals with the first isolation of Flexibacter maritimus from Senegalese sole, Solea senegalensis (Kaup…