ERBB2 protein, human

Known as: ERBB2 Receptor Protein-Tyrosine Kinase, Proto-Oncogene Neu, ERBB2 
A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer cells removed from the body… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Patients with breast cancer along with metastatic estrogen and progesterone receptor (ER/PR)- and human epidermal growth factor… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Preclinical studies in ErbB2-positive cell lines demonstrated a synergistic interaction between lapatinib and trastuzumab… (More)
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Highly Cited
2004
Highly Cited
2004
We have determined the 3.2 A X-ray crystal structure of the extracellular domain of the human epidermal growth factor receptor 2… (More)
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Highly Cited
2004
Highly Cited
2004
The protein-kinase family is the most frequently mutated gene family found in human cancer and faulty kinase enzymes are being… (More)
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Highly Cited
2002
Highly Cited
2002
Amplification of the gene encoding the ErbB2 (Her2/neu) receptor tyrosine kinase is critical for the progression of several forms… (More)
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Review
2001
Review
2001
When epidermal growth factor and its relatives bind the ErbB family of receptors, they trigger a rich network of signalling… (More)
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Highly Cited
2001
Highly Cited
2001
Both ErbB1 and ErbB2 are overexpressed or amplified in breast tumours. To examine the effects of activating ErbB receptors in a… (More)
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Highly Cited
1995
Highly Cited
1995
THE receptor erbB2/neu is a member of the epidermal growth factor receptor (EGFR or erbB) family that also includes erbB3 and… (More)
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Highly Cited
1986
Highly Cited
1986
A novel v-erb-B-related gene, c-erb-B-2, which has been identified in the human genome1,2, maps to human chromosome 17 at q21… (More)
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Highly Cited
1983
Highly Cited
1983
The topic of this report is rap,d m,croscale methods for ,solat,on of plant D N A without tile use of ul tracentr ,fugatlon wEth… (More)
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