Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Quinazolines

Known as: Quinazoline, Quinazolines [Chemical/Ingredient] 
 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (46)

10-formyl-5,8-10-trideazafolic acid2,4-dibenzylaminoquinazoline3,4-dihydroquinazoline dihydrochloride4-methyl-2-quinazolinamine
Expand
Prazosinantagonists & inhibitorschemical synthesis

Broader (1)

benzodiazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The ErbB/HER family of protein-tyrosine kinases and cancer.
  • R. Roskoski
  • Pharmacological research
  • 2014
    • Corpus ID: 12196199
The human epidermal growth factor receptor (EGFR) family consists of four members that belong to the ErbB lineage of proteins… Expand
  • figure 1
  • table 1
  • table 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Synthesis and in vitro antitumor activity of substituted quinazoline and quinoxaline derivatives: search for anticancer agent.
The synthesis of some 2-furano-4(3H)-quinazolinones, diamides (open ring quinazolines), quinoxalines and their biological… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
The clinical efficacy of epidermal growth factor receptor (EGFR) kinase inhibitors in EGFR-mutant non-small-cell lung cancer… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
Genetic alterations in the kinase domain of the epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
17β-Estradiol, Genistein, and 4-Hydroxytamoxifen Induce the Proliferation of Thyroid Cancer Cells through the G Protein-Coupled Receptor GPR30
The higher incidence of thyroid carcinoma (TC) in women during reproductive years compared with men and the increased risk… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize… Expand
  • table 1
  • table 2
  • figure 2
  • table 3
  • figure 3
Is this relevant?
Review
2003
Review
2003
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
Observations of functional adenosine triphosphate (ATP)-dependent drug efflux in certain multidrug-resistant cancer cell lines… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.
The epidermal growth factor receptor (EGFR) is commonly overexpressed in many human tumors and provides a new target for… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor.
Transforming growth factor alpha (TGF-alpha) is an autocrine growth factor for human cancer. Overexpression of TGF-alpha and its… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Structure-activity relationships of novel 2-substituted quinazoline antibacterial agents.
High-throughput screening of in-house compound libraries led to the discovery of a novel antibacterial agent, compound 1 (MIC: 12… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE