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Quinazolines

Known as: Quinazoline, Quinazolines [Chemical/Ingredient] 
National Institutes of Health

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50 relations

Narrower (46)

10-formyl-5,8-10-trideazafolic acid2,4-dibenzylaminoquinazoline3,4-dihydroquinazoline dihydrochloride4-methyl-2-quinazolinamine
Prazosinantagonists & inhibitorschemical synthesis

Broader (1)

benzodiazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The ErbB/HER family of protein-tyrosine kinases and cancer.
  • R. Roskoski
  • Pharmacological Research
  • 2014
  • Corpus ID: 12196199
Review
2012
Review
2012
EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications.
Highly Cited
2009
Highly Cited
2009
Four-component domino reaction leading to multifunctionalized quinazolines.
A new four-component domino reaction has been discovered. The reaction is easy to perform simply by mixing four common reactants… 
Highly Cited
2009
Highly Cited
2009
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
The clinical efficacy of epidermal growth factor receptor (EGFR) kinase inhibitors in EGFR-mutant non-small-cell lung cancer… 
Highly Cited
2008
Highly Cited
2008
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
Genetic alterations in the kinase domain of the epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC… 
Highly Cited
2005
Highly Cited
2005
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize… 
Review
2003
Review
2003
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
Observations of functional adenosine triphosphate (ATP)-dependent drug efflux in certain multidrug-resistant cancer cell lines… 
Review
2001
Review
2001
Quinoline, quinazoline and acridone alkaloids.
  • J. Michael
  • Natural product reports (Print)
  • 2001
  • Corpus ID: 2459722
Covering: July 2005 to June 2006. Previous review: Nat. Prod. Rep., 2007, 24, 223–246 This review covers the isolation… 
Review
2001
Review
2001
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.
The epidermal growth factor receptor (EGFR) autocrine pathway contributes to a number of processes important to cancer… 
Highly Cited
2000
Highly Cited
2000
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor.
Transforming growth factor alpha (TGF-alpha) is an autocrine growth factor for human cancer. Overexpression of TGF-alpha and its… 
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