Prazosin

Known as: 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline, Prazosine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline 
A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive. Prazosin's effects are most… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
BACKGROUND Current medications for alcohol dependence (AD) show only modest efficacy. None target brain noradrenergic pathways… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND Prazosin, a central nervous system (CNS) active alpha-1 adrenoreceptor antagonist, has reduced nightmares and sleep… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Intrinsic sensitivity of newly diagnosed chronic myeloid leukemia (CML) patients to imatinib (IC50(imatinib)) correlates with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
OBJECTIVE Prazosin is a centrally active alpha(1) adrenergic antagonist. The authors' goal was to evaluate prazosin efficacy for… (More)
  • table 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Little is known about the mechanisms converting psychosocial stress into cellular dysfunction. Various genes, up-regulated in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
P-glycoprotein is a plasma membrane protein of mammalian cells that confers multidrug resistance by acting as a broad-specificity… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Myocardial sympathetic activity is increased in heart failure. We tested the hypothesis that norepinephrine (NE… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1993
Highly Cited
1993
BACKGROUND Characteristics such as age and race are often cited as determinants of the response of blood pressure to specific… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The aim of this study was to determine whether insulin sensitivity measured by the euglycaemic insulin clamp technique is lower… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
Is this relevant?
Highly Cited
1980
Highly Cited
1980
During norepinephrine release elecited by the arrival of nerve impulses, the neurotransmitter interacts with specific receptors… (More)
Is this relevant?