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Prazosin

Known as: 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline, Prazosine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline 
A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive. Prazosin's effects are most… 
National Institutes of Health

Related topics

Related topics

36 relations

Broader (4)

Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAntihypertensive Agentspiperazine
Adrenergic alpha-Antagonists [MoA]Arterial Vasodilation [PE]Decreased Blood Pressure [PE]Drug Allergy

Narrower (13)

HytrinL 765314MinipressMinizide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Effects of Intrathecal α1- and α2-Noradrenergic Agonists and Norepinephrine on Locomotion in Chronic Spinal Cats
Chau, Connie, Hugues Barbeau, and Serge Rossignol. Effects of intrathecal α1- and α2-noradrenergic agonists and norepinephrine on… 
Highly Cited
1994
Highly Cited
1994
Sympathetic mediation of peripheral vasodilation induced by spinal cord stimulation: animal studies of the role of cholinergic and adrenergic receptor subtypes.
Electric spinal cord stimulation (SCS) is widely used as a treatment modality for ischemic pain in peripheral arterial… 
Highly Cited
1993
Highly Cited
1993
Adrenergic excitation of cutaneous nociceptors in chronically inflamed rats
Highly Cited
1992
Highly Cited
1992
Memory-enhancing effects of post-training dipivefrin and epinephrine: Involvement of peripheral and central adrenergic receptors
Highly Cited
1987
Highly Cited
1987
Alpha 1-adrenoceptor activation elevates cytosolic calcium in rat pinealocytes by increasing net influx.
Highly Cited
1986
Highly Cited
1986
The vasoconstrictor effect of neuropeptide Y and related peptides in the guinea pig isolated heart
Highly Cited
1985
Highly Cited
1985
Postsynaptic alpha 2-noradrenergic receptors mediate feeding induced by paraventricular nucleus injection of norepinephrine and clonidine.
Highly Cited
1984
Highly Cited
1984
Characterization of alpha1 adrenergic receptors in human benign prostatic hyperplasia.
Highly Cited
1981
Highly Cited
1981
Molecular mechanisms involved in α-adrenergic responses
Highly Cited
1981
Highly Cited
1981
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
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