piperazine

Known as: Piperazin, 1,4-piperazine, Diethylenediamine 
 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (18)

1-(3-chlorophenyl)piperazineDMP 777DiethylcarbamazineFlunarizine
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Broader (4)

Antinematodal AgentsHeterocyclic Compounds, 1-RingPiperazinesnitrogenous heterocyclic compound
Piperazine citratePiperazine phosphatemecoproppiperazine adipate
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Papers overview

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Review
2009
Review
2009
Mechanism of action of and resistance to quinolones
Fluoroquinolones are an important class of wide-spectrum antibacterial agents. The first quinolone described was nalidixic acid… (More)
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Highly Cited
2007
Highly Cited
2007
A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I…
Insulin-like growth factor-I receptor (IGF-IR) and its ligands, IGF-I and IGF-II, are up-regulated in a variety of human cancers… (More)
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Highly Cited
2007
Highly Cited
2007
Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from…
BACKGROUND Ranolazine, a piperazine derivative, reduces ischemia via inhibition of the late phase of the inward sodium current… (More)
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Highly Cited
2005
Highly Cited
2005
N-Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’)
3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’) is an illicit drug that stimulates the release of serotonin (5-HT) and… (More)
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2004
2004
Discriminating between intra-and extracellular metals using chemical extractions : an update on the case of iron
Iron influences the climate system by limiting primary productivity. It is therefore essential to accurately measure the iron… (More)
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Review
2001
Review
2001
Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market.
1-Aryl-piperazine compounds are, depending on their substituents, selective for certain serotonin receptors and together with… (More)
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Highly Cited
1998
Highly Cited
1998
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.
There are many examples of a single receptor coupling directly to more than one cellular signal transduction pathway. Although… (More)
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Highly Cited
1998
Highly Cited
1998
Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection
Trypanosoma cruzi is the causative agent of Chagas' disease. The major protease, cruzain, is a target for the development of new… (More)
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Highly Cited
1989
Highly Cited
1989
Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.
The piperazine-type 5-hydroxytryptamine (5-HT) agonists 1-(m-trifluoromethylphenyl)piperazine (TFMPP), 1-(m-chlorophenyl… (More)
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Highly Cited
1974
Highly Cited
1974
Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.
Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization… (More)
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