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Flunarizine

Known as: Flunarizina, Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)-, Flunarizin 
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (5)

AnticonvulsantsCalcium Channel BlockersHistamine H1 AntagonistsVasodilator Agents

Narrower (3)

Flunarizine HydrochlorideGBR 13069Sibelium
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
Highly Cited
1990
Highly Cited
1990
Role of the excitotoxic mechanism in the development of neuronal damage following repeated brief cerebral ischemia in the gerbil: protective effects of MK-801 and pentobarbital
1990
1990
Effects of divalent cations on lipid flip-flop in the human erythrocyte membrane.
1987
1987
Relative sensitivities of chromaffin cell calcium channels to organic and inorganic calcium antagonists
1986
1986
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation
1986
1986
Isolated rat cardiac myocytes as an experimental model to study calcium overload: the effect of calcium-entry blockers.
Highly Cited
1985
Highly Cited
1985
Inhibition of smooth muscle cell proliferation and endothelial permeability with flunarizine in vitro and in experimental atheromas
SummaryRepeated weak electrical stimulations of rabbit carotid artery walls with implanted electrodes cause intimal… 
1982
1982
Local anaesthetic activity of organic calcium antagonists: relevance to their actions on smooth muscle.
Highly Cited
1979
Highly Cited
1979
Effects of some anti-epileptic, neuroleptic and gabaminergic drugs on convulsions induced by D,L-allyglycine
Highly Cited
1978
Highly Cited
1978
Effect of flunarizine on calcium-induced responses of peripheral vascular smooth muscle.
Flunarizine, a difluoro derivative of cinnarizine, is a potent inhibitor of Ca2+-induced constriction of isolated arteries; this… 
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