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Flunarizine

Known as: Flunarizina, Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)-, Flunarizin 
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (5)

AnticonvulsantsCalcium Channel BlockersHistamine H1 AntagonistsVasodilator Agents

Narrower (3)

Flunarizine HydrochlorideGBR 13069Sibelium
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Review
2003
Review
2003
Perinatal brain damage--from pathophysiology to prevention.
Highly Cited
2002
Highly Cited
2002
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.
PURPOSE To determine whether topical application of flunarizine reduces intraocular pressure (IOP) and acts as a retinal… 
Highly Cited
1990
Highly Cited
1990
Role of the excitotoxic mechanism in the development of neuronal damage following repeated brief cerebral ischemia in the gerbil: protective effects of MK-801 and pentobarbital
Highly Cited
1988
Highly Cited
1988
Calcium channel antagonists increase morphine-induced analgesia and antagonize morphine tolerance.
Highly Cited
1988
Highly Cited
1988
Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists.
Highly Cited
1987
Highly Cited
1987
Flunarizine reduces cerebral infarct size after photochemically induced thrombosis in spontaneously hypertensive rats.
The cerebroprotective effect of flunarizine was studied in a minimally invasive model of photochemically induced cerebral… 
Highly Cited
1986
Highly Cited
1986
A Placebo-Controlled, Double-Blind, Cross-Over Trial of Flunarizine in Common Migraine
After four weeks of medication-free baseline observation, 29 patients with common migraine randomly received flunarizine (10 mg… 
Highly Cited
1983
Highly Cited
1983
Flunarizine, a Calcium Channel Blocker, in the Prophylactic Treatment of Migraine
SYNOPSIS 
Highly Cited
1979
Highly Cited
1979
Effects of some anti-epileptic, neuroleptic and gabaminergic drugs on convulsions induced by D,L-allyglycine
Highly Cited
1978
Highly Cited
1978
Effect of flunarizine on calcium-induced responses of peripheral vascular smooth muscle.
Flunarizine, a difluoro derivative of cinnarizine, is a potent inhibitor of Ca2+-induced constriction of isolated arteries; this… 
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