Histamine H1 Antagonists

Known as: Antagonists, Histamine H1, H1 Antagonists, Histamine, Antihistaminics, H1 
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1944-2017
05010015019442016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
The atypical antipsychotic drugs (AAPDs) have markedly enhanced the treatment of schizophrenias but their use has been hindered… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Histamine is an important inflammatory mediator that is released in airways during an asthmatic response. However, current… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
We characterized human SirT1, one of the human homologs of the budding yeast Sir2p, an NAD+-dependent histone deacetylase… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Mutations in the HERG K(+) channel gene cause inherited long QT syndrome (LQT), a disorder of cardiac repolarization that… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The linker histone H1 is believed to be involved in chromatin organization by stabilizing higher-order chromatin structure… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The considerable length of DNA in eukaryotic genomes requires packaging into chromatin to fit inside the small dimensions of the… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Cyclin-dependent kinase 5 (CDK5) is a unique CDK, the activity of which can be detected in postmitotic neurons. To date, CDK5… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Fexofenadine, a nonsedating antihistamine, does not undergo significant metabolic biotransformation. Accordingly, it was… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1986
1986
Graded dose of the histamine H1 antagonists tripelennamine (0.1-3.0 mg/kg), promethazine (0.1-3.0 mg/kg), diphenhydramine (0.3-10… (More)
Is this relevant?