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Histamine H1 Antagonists
Known as:
Antagonists, Histamine H1
, H1 Antagonists, Histamine
, Antihistaminics, H1
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Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are…
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National Institutes of Health
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Related topics
Related topics
49 relations
Narrower (40)
Antazoline
Azelastine hydrochloride
Cinnarizine
Clemastine
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Anti-Allergic Agents
Bronchodilator Agents
Hypnotics and Sedatives
Immediate hypersensitivity
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Broader (2)
Antihistamines
Histamine Antagonists
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Structure of the human histamine H1 receptor complex with doxepin
T. Shimamura
,
M. Shiroishi
,
+10 authors
S. Iwata
Nature
2011
Corpus ID: 4413987
The biogenic amine histamine is an important pharmacological mediator involved in pathophysiological processes such as allergies…
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Highly Cited
2007
Highly Cited
2007
A Pseudo-Response Regulator is misexpressed in the photoperiod insensitive Ppd-D1a mutant of wheat (Triticum aestivum L.)
J. Beales
,
A. Turner
,
S. Griffiths
,
J. Snape
,
D. Laurie
Theoretical and Applied Genetics
2007
Corpus ID: 10270019
Ppd-D1 on chromosome 2D is the major photoperiod response locus in hexaploid wheat (Triticum aestivum). A semi-dominant mutation…
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Highly Cited
2005
Highly Cited
2005
The Pseudo-Response Regulator Ppd-H1 Provides Adaptation to Photoperiod in Barley
A. Turner
,
J. Beales
,
S. Faure
,
R. Dunford
,
D. Laurie
Science
2005
Corpus ID: 45667495
Plants commonly use photoperiod (day length) to control the timing of flowering during the year, and variation in photoperiod…
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Highly Cited
2004
Highly Cited
2004
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin.
A. Vaquero
,
Michael B Scher
,
Donghoon Lee
,
H. Erdjument-Bromage
,
P. Tempst
,
D. Reinberg
Molecular cell
2004
Corpus ID: 34781312
Highly Cited
2002
Highly Cited
2002
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
M. Krendel
,
F. Zenke
,
G. Bokoch
Nature Cell Biology
2002
Corpus ID: 25681168
Regulation of the actin cytoskeleton by microtubules is mediated by the Rho family GTPases. However, the molecular mechanisms…
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Highly Cited
2000
Highly Cited
2000
Dynamic binding of histone H1 to chromatin in living cells
T. Misteli
,
A. Gunjan
,
R. Hock
,
M. Bustin
,
David T. Brown
Nature
2000
Corpus ID: 4428934
The linker histone H1 is believed to be involved in chromatin organization by stabilizing higher-order chromatin structure…
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Highly Cited
1999
Highly Cited
1999
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.
M. Cvetković
,
B. Leake
,
M. Fromm
,
G. Wilkinson
,
R. Kim
Drug metabolism and disposition: the biological…
1999
Corpus ID: 6713092
Fexofenadine, a nonsedating antihistamine, does not undergo significant metabolic biotransformation. Accordingly, it was…
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Highly Cited
1995
Highly Cited
1995
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
J. He
,
S. Choe
,
R. Walker
,
P. Di Marzio
,
D. Morgan
,
N. Landau
Journal of virology
1995
Corpus ID: 23763175
The Vpr accessory gene product of human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus is believed to…
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Highly Cited
1991
Highly Cited
1991
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily.
P. Jones
,
T. Jakubowicz
,
F. Pitossi
,
F. Maurer
,
B. Hemmings
Proceedings of the National Academy of Sciences…
1991
Corpus ID: 25076009
A partial cDNA was isolated that encoded a protein kinase, termed rac (related to the A and C kinases). This cDNA was…
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Highly Cited
1988
Highly Cited
1988
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
G. Di Chiara
,
A. Imperato
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 10433223
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus…
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