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Histamine H1 Antagonists

Known as: Antagonists, Histamine H1, H1 Antagonists, Histamine, Antihistaminics, H1 
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (40)

AntazolineAzelastine hydrochlorideCinnarizineClemastine
Anti-Allergic AgentsBronchodilator AgentsHypnotics and SedativesImmediate hypersensitivity

Broader (2)

AntihistaminesHistamine Antagonists

Papers overview

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Highly Cited
1986
Highly Cited
1986
Rapid microassay for protein kinase C translocation in Swiss 3T3 cells.
The Ca2+/phosphatidylserine-stimulated protein kinase C (PKC) appears to exist as interconvertible inactive, soluble and active… 
1985
1985
New antihistaminic N-heterocyclic 4-piperidinamines. 3. Synthesis and antihistaminic activity of N-(4-piperidinyl)-3H-imidazo[4,5-b]pyridin-2-amines.
To study the bioisosteric replacement of a 2-pyridyl ring for a phenyl nucleus in astemizole, a series of N-(4-piperidinyl)-3H… 
Highly Cited
1983
Highly Cited
1983
Isolation, identification, and characterization of histones from plasmodia of the true slime mold Physarum polycephalum using extraction with guanidine hydrochloride.
Histones from plasmodia of the true slime mold Physarum polycephalum have been prepared free of slime by an approach to histone… 
Highly Cited
1982
Highly Cited
1982
Isolation and characterization of coaggregation-defective mutants of Actinomyces viscosus, Actinomyces naeslundii, and Streptococcus sanguis
Spontaneously occurring coaggregation-defective (COG-) mutants of oral actinomycetes and streptococci were isolated and used to… 
Highly Cited
1979
Highly Cited
1979
Reassociation of histone H1 with nucleosomes.
The role of histone H1 in nucleosome heterogeneity and structure has been studied using a reconstitution procedure. Histone H1… 
Highly Cited
1976
Highly Cited
1976
Conformational changes in subfractions of calf thymus histone H1.
This paper presents the first study of conformational changes in the subfractions of calf thymus H1. H1 was fractionated by the… 
Highly Cited
1975
Highly Cited
1975
Effect of antihistamine-antiserotonin and ganglionic blocking agents upon increased capillary permeability following burn trauma.
Tiny (0.2% TBS), partial thickness, non-contact radiant heat burns in guinea pigs resulted, within 3 hours, in significant edema… 
1972
1972
Genetic analysis of fla and mot cistrons closely linked to H1 in Salmonella abortusequi and its derivatives.
Summary: Spontaneous non-flagellate and paralysed mutants were isolated from a phase-1 stable strain of Salmonella abortusequi… 
1966
1966
Sulphuric Esters of Polysaccharides as Activators of a Bradykinin-forming System in Plasma
PREVIOUS work1 has shown that intravenous injection of agar, a naturally occurring sulphuric ester of polygalactose, leads to an… 
1949
1949
Some pharmacological properties common to antihistamine compounds.