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Diethylcarbamazine

Known as: Diéthylcarbamazine, Diethylcarbamazine [Chemical/Ingredient], Dietilcarbamazina 
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
National Institutes of Health

Related topics

Related topics

17 relations

Broader (4)

AnthelminticsFilaricidesLipoxygenase Inhibitorspiperazine

Narrower (6)

CaminDiethylcarbamazine CitrateHetrazanLoxuran
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Detection of codon for amino acid 200 in isotype 1 beta-tubulin gene of Wuchereria bancrofti isolates, implicated in resistance to benzimidazoles in other nematodes.
2001
2001
Severe hepatic involvement in visceral larva migrans.
Highly Cited
1995
Highly Cited
1995
Differential decline in filaria-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy.
In human filariasis, the predominant serum antibody is IgG4, accompanied by significant IgE production. The ratio of IgG4 to IgE… 
1990
1990
Oxygen free radical producing leukocytes cause functional depression of isolated rat hearts: role of leukotrienes.
Highly Cited
1979
Highly Cited
1979
Diethylcarbamazine enhances antibody-mediated cellular adherence to Brugia malayi microfilariae
Treatment with the antifilarial drug diethylcarbamazine (DEC) results in a rapid decline in the number of microfilariae… 
Highly Cited
1976
Highly Cited
1976
Onchocercal dermatitis: ultrastructural studies of microfilariae and host tissues, before and after treatment with diethylcarbamazine (Hetrazan).
Specimens of skin from four Cameroon patients with severe onchocercal dermatitis, before and after treatment with… 
Review
1975
Review
1975
Tropical eosinophilia. A human model of parasitic immunopathology, with observations on serum IgE levels before and after treatment.
Highly Cited
1970
Highly Cited
1970
Onchocerciasis. Onchocercal dermatitis, lymphadenitis, and elephantiasis in the Ubangi territory.
Highly Cited
1968
Highly Cited
1968
Inhibition of the Release of Slow-Reacting Substance of Anaphylaxis in the Rat with Diethylcarbamazine∗
Summary The immunologic release of SRS-Arat with intravenously administered antigen is described. Hetrazan effectively inhibits… 
Highly Cited
1961
Highly Cited
1961
The first record of an outbreak of trichinosis in Africa south of the Sahara.
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