Tykerb
National Institutes of Health
Papers overview
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AIM
The poor water solubility of many active compounds is a serious deterrent to their use as commercial drugs. Lapatinib is a…
Abstract Protein kinases catalyse key phosphorylation reactions in signalling cascades that affect every aspect of cell growth…
Lapatinib is active at the ATP-binding site of tyrosine kinases that are associated with the human epidermal growth factor…