Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Tykerb

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

lapatiniblapatinib ditosylate
lapatinib Oral Tablet [Tykerb]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Incorporation of lapatinib into lipoprotein-like nanoparticles with enhanced water solubility and anti-tumor effect in breast cancer.
AIM The poor water solubility of many active compounds is a serious deterrent to their use as commercial drugs. Lapatinib is a… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Review
2009
Review
2009
Protein kinase inhibitors: contributions from structure to clinical compounds
  • L. Johnson
  • Quarterly Reviews of Biophysics
  • 2009
    • Corpus ID: 25148405
Abstract Protein kinases catalyse key phosphorylation reactions in signalling cascades that affect every aspect of cell growth… Expand
Highly Cited
2008
Highly Cited
2008
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
Lapatinib is active at the ATP-binding site of tyrosine kinases that are associated with the human epidermal growth factor… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
2008
2008
The Role of Efflux and Uptake Transporters in Lapatinib (Tykerb, GW572016) Disposition and Drug Interactions.
 
  • table 1
  • table 2
  • table 3
  • table 5
  • table 6
2008
2008
2 ATP-Binding Cassette Subfamily B Member 1 and G Member Resistance in Cancer Cells by Inhibiting the Activity of Lapatinib ( Tykerb , GW 572016 ) Reverses Multidrug
Lapatinib is active at the ATP-binding site of tyrosine kinases that are associated with the human epidermal growth factor… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE