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Tykerb

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

lapatiniblapatinib ditosylate
lapatinib Oral Tablet [Tykerb]

Papers overview

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2013
2013
Incorporation of lapatinib into lipoprotein-like nanoparticles with enhanced water solubility and anti-tumor effect in breast cancer.
AIM The poor water solubility of many active compounds is a serious deterrent to their use as commercial drugs. Lapatinib is a… Expand
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Review
2009
Review
2009
Protein kinase inhibitors: contributions from structure to clinical compounds.
Protein kinases catalyse key phosphorylation reactions in signalling cascades that affect every aspect of cell growth… Expand
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Highly Cited
2008
Highly Cited
2008
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
Lapatinib is active at the ATP-binding site of tyrosine kinases that are associated with the human epidermal growth factor… Expand
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2008
2008
The Role of Efflux and Uptake Transporters in Lapatinib (Tykerb, GW572016) Disposition and Drug Interactions.
 
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2008
2008
2 ATP-Binding Cassette Subfamily B Member 1 and G Member Resistance in Cancer Cells by Inhibiting the Activity of Lapatinib ( Tykerb , GW 572016 ) Reverses Multidrug
Lapatinib is active at the ATP-binding site of tyrosine kinases that are associated with the human epidermal growth factor… Expand
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