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In sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)-associated tuberculosis is high. We conducted… Expand BACKGROUND
Treatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and… Expand The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl carrier protein reductase (InhA), an… Expand Isoniazid (isonicotinic acid hydrazide, INH) is one of the most widely used antituberculosis drugs, yet its precise target of… Expand TUBERCULOSIS is responsible for one in four of all avoidable adult deaths in developing countries1. Increased frequency and… Expand ALT = serum alanine aminotransferase; AST serum aspartate aminotransferase; BIU bilirubin; EMB ethambutol; INH isoniazid; NSM not… Expand Diagnostic Criteria of Nontuberculous Mycobacterial Lung Disease For patients with a cavitary infiltrate: Two or more sputums or… Expand The clinical spectrum of isoniazid-induced liver injury seems to be clinically, biochemically, and histologically… Expand With a stepwise degradation and terminal labeling procedure the 3'-terminal sequence of E. coli 16S ribosomal RNA is shown to be… Expand collars limits their use to some extent" (Lancet, 1958). It has also been suggested that conservative treatment should not… Expand