gemcitabine

Known as: 2'-Deoxy-2',2'-difluorocytidine, dFdC, 2',2'-DFDC 
A broad-spectrum antimetabolite and deoxycytidine analogue with antineoplastic activity. Upon administration, gemcitabine is converted into the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND There is no established standard chemotherapy for patients with locally advanced or metastatic biliary tract cancer… (More)
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Highly Cited
2010
Highly Cited
2010
CONTEXT Adjuvant fluorouracil has been shown to be of benefit for patients with resected pancreatic cancer. Gemcitabine is known… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor, improves survival when combined with… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non-small-cell lung cancer (NSCLC… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT The role of adjuvant therapy in resectable pancreatic cancer is still uncertain, and no recommended standard exists… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Patients with advanced pancreatic cancer have a poor prognosis and there have been no improvements in survival since the… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Myeloid suppressor (Gr-1(+)/CD11b(+)) cells accumulate in the spleens of tumor-bearing mice where they contribute to… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE The purpose of this study was to determine whether the addition of the epidermal growth factor receptor tyrosine kinase… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE Gemcitabine plus cisplatin (GC) and methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) were compared in… (More)
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Highly Cited
1997
Highly Cited
1997
PURPOSE Most patients with advanced pancreas cancer experience pain and must limit their daily activities because of tumor… (More)
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