Gemcitabine hydrochloride

Known as: 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride, 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride, Difluorodeoxycytidine Hydrochloride 
The hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted… (More)

Topic mentions per year

Topic mentions per year

1994-2018
051019942018

Papers overview

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2012
2012
Gemcitabine is a deoxycytidine analog used in the treatment of various solid tumors. However, tumors often develop resistances… (More)
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2012
2012
Gemcitabine hydrochloride (HCl) is approved for the treatment of a wide spectrum of solid tumors. However, the rapid development… (More)
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2012
2012
Previously, it was shown that a novel 4-(N)-stearoyl gemcitabine nanoparticle formulation was more effective than gemcitabine… (More)
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2009
2009
Gemcitabine hydrochloride is an anticancer nucleoside analogue indicated in clinic for the treatment of various solid tumors… (More)
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2005
2005
The objective of this study was to evaluate the physical and chemical stability of undiluted palonosetron 50 micrograms/mL as the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Chemoresistance may involve the anti-apoptotic transcriptional regulator, nuclear factor-kappa B (NF-kappa B). The… (More)
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1999
1999
OBJECTIVE To evaluate the physical and chemical stability of gemcitabine hydrochloride (Gemzar-Eli Lilly and Company) solutions… (More)
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1996
1996
A late phase II study of LY188011 (gemcitabine hydrochloride), a new synthetic anticancer agent, was conducted at 20 Japanese… (More)
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1994
1994
Gemcitabine (2',2'-difluorodeoxycytidine monohydrochloride, LY188011 hydrochloride, CAS 122111-03-9) is a nucleoside analog with… (More)
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1994
1994
The anti-tumor agent gemcitabine hydrochloride, a beta-difluoronucleoside, is remarkably stable in the solid state. In 0.1 N HCI… (More)
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