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Gemcitabine hydrochloride

Known as: 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride, 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride, Difluorodeoxycytidine Hydrochloride 
The hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted… Expand
National Institutes of Health

Papers overview

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2016
2016
We synthesized agarose-polycaprolactone (Agr-PCL) bicomponent and Agr-polyethylene glycol-PCL (Agr-PEG-PCL) tricomponent… Expand
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2012
2012
Previously, it was shown that a novel 4-(N)-stearoyl gemcitabine nanoparticle formulation was more effective than gemcitabine… Expand
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2012
2012
Gemcitabine is a deoxycytidine analog used in the treatment of various solid tumors. However, tumors often develop resistances… Expand
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2012
2012
Gemcitabine hydrochloride (HCl) is approved for the treatment of a wide spectrum of solid tumors. However, the rapid development… Expand
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2009
2009
Gemcitabine hydrochloride is an anticancer nucleoside analogue indicated in clinic for the treatment of various solid tumors… Expand
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Highly Cited
2006
Highly Cited
2006
The interactions between gemcitabine hydrochloride (GEM) and bovine serum albumin (BSA) or human serum albumin (HSA) have been… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract Background. Chemoresistance may involve the anti-apoptotic transcriptional regulator, nuclear factor-κB (NF-κB). The… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Chemoresistance may involve the anti-apoptotic transcriptional regulator, nuclear factor-kappa B (NF-kappa B). The… Expand
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2000
2000
A study of the degradation kinetics of gemcitabine hydrochloride (2'-deoxy-2',2'-difluorocytidine) in aqueous solution at pH 3.2… Expand
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1999
1999
OBJECTIVE To evaluate the physical and chemical stability of gemcitabine hydrochloride (Gemzar-Eli Lilly and Company) solutions… Expand
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