• Publications
  • Influence
Study of the stability of tylosin A in aqueous solutions.
The decomposition of the 16-membered ring macrolide antibiotic tylosin A in aqueous buffers has been investigated in the pH range 2-13, by means of a liquid chromatographic assay with ultravioletExpand
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF CEFIXIME IN BULK DRUGS
A new technique for the quantitative determination of cefixime trihydrate in bulk drugs by high performance liquid chromatography was developed using simple reagents. Finally, chosen conditions ofExpand
The antiplasmodial activity of isolates from Ajuga remota.
TLDR
Both ajugarin-1 and ergosterol-5,8-endoperoxide did not exhibit cytotoxicity against A431 (skin carcinoma) cell line, but 8-O-acetylharpagide was significantly cytotoxic. Expand
Analysis of purity in 19 drug product tablets containing clopidogrel: 18 copies versus the original brand.
TLDR
Most of the copies were not similar compared to the original drug product: their amount of impurities was higher, the content of clopidogrel lower, the dissolution profiles different and after 3 months under stress conditions in the original packaging, the results for the samples and the reference were significantly different in most of the cases. Expand
Determination of capsaicinoids in topical cream by liquid-liquid extraction and liquid chromatography.
TLDR
A reversed-phase liquid chromatography method has been developed, optimised and validated for the separation and quantitation of capsaicin and dihydrocapsaicin in a topical cream formulation and shows good selectivity, linearity, sensitivity and repeatability. Expand
Racemization of aspartic acid from human dentin in the estimation of chronological age.
TLDR
In this review, results of aspartic acid racemization in dentin at different targets are discussed and pre-considerations and guidelines are given for the selection of dentin from teeth. Expand
Determination of stigmasterol, beta-sitosterol and stigmastanol in oral dosage forms using high performance liquid chromatography with evaporative light scattering detection.
TLDR
This method was used to assay commercially available products formulated as oral dosage forms purported to contain African Potato and associated sterols and stanol and proved to be suitable for the routine analysis and quality control of such products. Expand
Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Evaluation of 36 test parameters: repeatability, reproducibility and correlation.
TLDR
A test procedure was proposed that allows measurement of a number of parameters which are reported to be representative for stationary phase characteristics and applied on 69 RP-LC C18 columns. Expand
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.
TLDR
A quantitative nonisotopic solution assay for gelatinases and inhibitors was developed using biotinylated gelatin as enzyme substrate and the gelatinase B inhibitory activity of tetracyclines was clearly dissociated from their antimicrobial activity. Expand
WHO Expert Committee on Specifications for Pharmaceutical Preparations.
TLDR
The monographs on antiretrovirals proposed for inclusion in The International Pharmacopoeia and specifications for radiopharmaceuticals, quality specifications for antituberculosis drugs and the revision of the monograph on artemisinin derivatives are discussed. Expand
...
1
2
3
4
5
...