DNA Synthesis Inhibition

DNA Synthesis Inhibition involves interference with, or restraint of, the activities involved in the polymeric linkage of deoxyribose moieties (with… (More)
National Institutes of Health

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2008
2008
Bacteria infecting eukaryotic hosts often encounter therapeutic antimicrobial and DNA damaging agents and respond by forming… (More)
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2007
2007
Cell cycle checkpoint abrogation, especially the inhibition of Chk1 in combination with DNA-damaging treatments, has been… (More)
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2005
2005
In response to DNA damage, signaling pathways are triggered that either block the cell division cycle at defined transitions (G1… (More)
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2002
2002
Bloom's syndrome (BS) arises through mutations in both copies of the BLM gene that encodes a RecQ 3′-5′ DNA helicase. BS patients… (More)
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1998
1998
Positive results in the in vitro assay for chromosome aberrations sometimes occur with test chemicals that apparently do not… (More)
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1993
1993
The studies described herein were aimed at defining the mechanism by which 9-beta-D-arabinofuranosyl-2-fluoroadenine 5… (More)
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1983
1983
Core histone mRNA metabolism has been examined in S phase HeLa cells recovering from DNA synthesis inhibition by 1 mM hydroxyurea… (More)
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1977
1977
Neocarzinostatin inhibits DNA synthesis in HeLa S3 cells and induces the rapid limited breakage of cellular DNA. The… (More)
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1976
1976
1-β-D-ARABINOFURANOSYL CYTOSINE (ara-C) and 9-β-D-arabinofuranosyl adenine (ara-A) are potent antileukaemic and antiviral agents… (More)
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1971
1971
A specific endogenous inhibitor for lymphocyte DNA synthesis that can be isolated from the lymphoid system and which is probably… (More)
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