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DNA Synthesis Inhibition

DNA Synthesis Inhibition involves interference with, or restraint of, the activities involved in the polymeric linkage of deoxyribose moieties (with… Expand
National Institutes of Health

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2008
2008
Bacteria infecting eukaryotic hosts often encounter therapeutic antimicrobial and DNA damaging agents and respond by forming… Expand
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2007
2007
Cell cycle checkpoint abrogation, especially the inhibition of Chk1 in combination with DNA-damaging treatments, has been… Expand
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Highly Cited
2005
Highly Cited
2005
In response to DNA damage, signaling pathways are triggered that either block the cell division cycle at defined transitions (G1… Expand
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2003
2003
PurposeCytotoxicity from the anticancer drug 2′,2′-difluoro-2′-deoxycytidine (dFdCyd) has been correlated with its incorporation… Expand
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2002
2002
Bloom's syndrome (BS) arises through mutations in both copies of the BLM gene that encodes a RecQ 3′-5′ DNA helicase. BS patients… Expand
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Highly Cited
1998
Highly Cited
1998
Positive results in the in vitro assay for chromosome aberrations sometimes occur with test chemicals that apparently do not… Expand
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1993
1993
The studies described herein were aimed at defining the mechanism by which 9-beta-D-arabinofuranosyl-2-fluoroadenine 5… Expand
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1989
1989
We have compared the growth inhibition, DNA synthesis inhibition and cell incorporation of eight anthracyclines in a model of… Expand
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Highly Cited
1976
Highly Cited
1976
The synthesis of protein X (Inouye & Pardee, 1970) is switched on by the inhibition of DNA synthesis. This induction of protein X… Expand
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1971
1971
A specific endogenous inhibitor for lymphocyte DNA synthesis that can be isolated from the lymphoid system and which is probably… Expand
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