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DNA Synthesis Inhibition

DNA Synthesis Inhibition involves interference with, or restraint of, the activities involved in the polymeric linkage of deoxyribose moieties (with… 
National Institutes of Health

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5,6-dihydro-5-azacytidineBromodeoxyuridineDNADNA Minor Groove Binding Agent SG2000

Papers overview

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1998
1998
Kinetics of mouse jejunum radiosensitization by 2′,2′-difluorodeoxycytidine (gemcitabine) and its relationship with pharmacodynamics of DNA synthesis inhibition and cell cycle redistribution in crypt…
V Gr6goire, M Beauduin, J-F Rosier, B De Coster, M Bruiaux, M Octave-Prignot and P Scalliet Br] JCtmcer- 76: 1315-1321 Due to an… 
1992
1992
Increase in Cytoplasmic Casein Kinase II‐Type Activity Accompanies Neurite Outgrowth After DNA Synthesis Inhibition in NIA‐103 Neuroblastoma Cells
Abstract: Whereas cells from most clonal lines derived from the murine neuroblastoma C1300 tumor can be induced to differentiate… 
1990
1990
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay
The chemosensitivities of primary tumors (PT) and simultaneous metastatic lymph nodes (MN) to mitomycin C (MMC), 5‐fluorouracil… 
1988
1988
Growth and DNA synthesis inhibition and superoxide anion formation by iminoquinones in Trypanosoma cruzi
Despite its epidemiological importance, chemotherapy of Chagas' disease is still an unsolved problem. Many drugs have been… 
1986
1986
Pre-screening of carcinogens by studying of DNA synthesis inhibition and gene mutations in mammalian cells.
The ability to induce gene mutations at the HGPRT locus in Chinese hamster V79 cells and to inhibit DNA synthesis in human EUE… 
1986
1986
Induction of DNA single-strand breaks and DNA synthesis inhibition in CHO and AWRF cells after exposure to sterigmatocystin and penicillic acid.
Sterigmatocystin is 12 times more toxic to transformed rat fibroblasts (AWRF) than to Chinese hamster ovary cells (CHO). In… 
1978
1978
DNA synthesis inhibition in HeLa cells as a simple test for agents that damage human DNA.
Inhibition of HeLa cell DNA synthesis by DNA-damaging agents as a test for mutagenic carcinogens has been investigated further… 
Highly Cited
1977
Highly Cited
1977
The relationship between DNA strand-scission and DNA synthesis inhibition in HeLa cells treated with neocarzinostatin.
1973
1973
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Four groups of Wistar rats were treated with 100 mg/kg aminothiadiazole (ATD) i.p. on day 12 of gestation. The first group was… 
1969
1969
Initiation of DNA replication cycles in Escherichia coli following DNA synthesis inhibition.
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