gabapentin

Known as: gabapentin [Chemical/Ingredient], Gabapentina, Convalis 
A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Review
2006
Review
2006
Gabapentin and pregabalin are structurally related compounds with recognized efficacy in the treatment of both epilepsy and… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND A combination of opioid and nonopioid analgesic drugs may improve the quality of postoperative analgesia as well as… (More)
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Review
2002
Review
2002
Although its exact mode of action is not known, gabapentin appears to have a unique effect on voltage-dependent calcium ion… (More)
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Highly Cited
2002
Highly Cited
2002
Gabapentin and pregabalin (S-(+)-3-isobutylgaba) produced concentration-dependent inhibitions of the K(+)-induced [Ca(2+)](i… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The anticonvulsant gabapentin has proven effective for neuropathic pain in three large placebo-controlled clinical… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To compare gabapentin with placebo for use as a prophylactic agent in patients with migraine (with or without aura… (More)
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Review
1998
Review
1998
Although the cellular mechanisms of pharmacological actions of gabapentin (Neurontin) remain incompletely described, several… (More)
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Highly Cited
1996
Highly Cited
1996
Gabapentin (1-(aminomethyl)cyclohexane acetic acid; Neurontin) is a novel anticonvulsant drug, with a mechanism of action… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVE This is a report of a trial of the new antiepileptic agent gabapentin in patients with intractable neuropathic pain… (More)
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