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gabapentin

Known as: gabapentin [Chemical/Ingredient], Gabapentina, Convalis 
A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown… 
National Institutes of Health

Related topics

Related topics

31 relations

Broader (9)

AminesAnalgesicsAnti-Anxiety AgentsAnticonvulsants
Antidepressive AgentsAntiepileptic AgentsBipolar DisorderCalcium Channel Blockers

Narrower (3)

GraliseHorizantNeurontin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Validation of LC-TOF-MS screening for drugs, metabolites, and collateral compounds in forensic toxicology specimens.
Liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS) analysis provides an expansive technique for identifying many… 
Highly Cited
2010
Highly Cited
2010
Pharmacological recruitment of the GABAergic tail of the ventral tegmental area by acute drug exposure
BACKGROUND AND PURPOSE The tail of the ventral tegmental area (tVTA), also called the rostromedial tegmental nucleus, is a newly… 
Highly Cited
2008
Highly Cited
2008
Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin
Gabapentin absorption occurs in only a limited region of the small intestine and saturates at doses used clinically, resulting in… 
Highly Cited
2006
Highly Cited
2006
Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury
Highly Cited
2005
Highly Cited
2005
Polypeptide helices in hybrid peptide sequences.
A new class of polypeptide helices in hybrid sequences containing alpha-, beta-, and gamma-residues is described. The molecular… 
Highly Cited
2005
Highly Cited
2005
An epidemiological investigation of off‐label anticonvulsant drug use in the Georgia Medicaid population
The primary objective was to determine the prevalence of off‐label anticonvulsant drug use in the Georgia Medicaid population and… 
Highly Cited
2001
Highly Cited
2001
Treatment of idiopathic restless legs syndrome (RLS) with gabapentin
Nine patients with idiopathic restless legs syndrome (RLS) were treated with 300 mg of gabapentin as an initial dose and an up… 
Highly Cited
2000
Highly Cited
2000
Antiallodynic Effect of Intrathecal Gabapentin and Its Interaction with Clonidine in a Rat Model of Postoperative Pain
Background: Systemic administration of gabapentin was shown previously to attenuate mechanical allodynia in a rat model of… 
Highly Cited
1999
Highly Cited
1999
Gabapentin for the Treatment of Postherpetic Neuralgia
Background: The goal of this study was to evaluate the effects of gabapentin on postherpetic neuralgia. Gabapentin is a known… 
Review
1999
Review
1999
Lamotrigine in the treatment of bipolar depression
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