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gabapentin

Known as: gabapentin [Chemical/Ingredient], Gabapentina, Convalis 
A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown… 
National Institutes of Health

Related topics

Related topics

31 relations

Broader (9)

AminesAnalgesicsAnti-Anxiety AgentsAnticonvulsants
Antidepressive AgentsAntiepileptic AgentsBipolar DisorderCalcium Channel Blockers

Narrower (3)

GraliseHorizantNeurontin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pharmacological recruitment of the GABAergic tail of the ventral tegmental area by acute drug exposure
BACKGROUND AND PURPOSE The tail of the ventral tegmental area (tVTA), also called the rostromedial tegmental nucleus, is a newly… 
Highly Cited
2010
Highly Cited
2010
Gabapentin Extended-Release Tablets for the Treatment of Patients with Postherpetic Neuralgia
AbstractBackground: Postherpetic neuralgia (PHN) is a neuropathic pain syndrome that may develop subsequent to healing of herpes… 
Highly Cited
2008
Highly Cited
2008
Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin
Gabapentin absorption occurs in only a limited region of the small intestine and saturates at doses used clinically, resulting in… 
Highly Cited
2006
Highly Cited
2006
Prophylactic gabapentin for prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled study.
BACKGROUND Gabapentin is an antiepileptic drug. Its antiemetic effect is demonstrated in chemotherapy-induced acute and delayed… 
Highly Cited
2006
Highly Cited
2006
The effect of gabapentin on post‐operative pain following tonsillectomy in adults
Background:  The aim of the present study was to investigate whether a combination of rofecoxib and gabapentin could improve pain… 
Highly Cited
2005
Highly Cited
2005
Polypeptide helices in hybrid peptide sequences.
A new class of polypeptide helices in hybrid sequences containing alpha-, beta-, and gamma-residues is described. The molecular… 
Highly Cited
2005
Highly Cited
2005
An epidemiological investigation of off‐label anticonvulsant drug use in the Georgia Medicaid population
The primary objective was to determine the prevalence of off‐label anticonvulsant drug use in the Georgia Medicaid population and… 
2004
2004
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain
Review
2003
Review
2003
Treatment of symptomatic diabetic neuropathy
Painful diabetic neuropathy is a common and particularly unpleasant long‐term complication of diabetes that affects a significant… 
Highly Cited
2000
Highly Cited
2000
Antiallodynic Effect of Intrathecal Gabapentin and Its Interaction with Clonidine in a Rat Model of Postoperative Pain
Background: Systemic administration of gabapentin was shown previously to attenuate mechanical allodynia in a rat model of… 
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