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Diabetic neuropathies: a statement by the American Diabetes Association.
Not all patients with peripheral nerve dysfunction have a neuropathy caused by diabetes, and effective symptomatic treatments are available for the manifestations of DPN and autonomic neuropathy.
The global burden of diabetic foot disease
When assessing the economic effects of diabetic foot disease, it is important to remember that rates of recurrence of foot ulcers are very high, being greater than 50% after 3 years.
Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments
Preceding the joint meeting of the 19th annual Diabetic Neuropathy Study Group of the European Association for the Study of Diabetes (NEURODIAB) and the 8th International Symposium on Diabetic…
Diabetic somatic neuropathies.
This review will discuss the clinical features, assessment, and management of the patient with the most common form of DN, diabetic distal sensory polyneuropathy (DPN), and the late sequelae of DPN and their prevention.
Diabetic Neuropathy: A Position Statement by the American Diabetes Association
Although screening for rarer atypical forms of diabetic neuropathy may be warranted, DSPN and autonomic neuropathy are the most common forms encountered in practice and the strongest available evidence regarding treatment pertains to these forms.
Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings.
The most frequent component causes for lower-extremity ulcers were trauma, neuropathy, and deformity, which were present in a majority of patients, and clinics are encouraged to use proven strategies to prevent and decrease the impact of modifiable conditions leading to foot ulcers in patients with diabetes.
Comprehensive foot examination and risk assessment. A report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of…
As physical therapy, podiatric medicine and identification of those patients at risk of foot problems is the first step in preventing such complications, this report will focus on key components of the foot exam.
The diabetic foot: from art to science. The 18th Camillo Golgi lecture
- A. Boulton
- 28 July 2004
It is hoped that increasing research activity in foot disease will ultimately result in fewer ulcers and less amputation in diabetes.
A role for mitogen‐activated protein kinases in the etiology of diabetic neuropathy
- T. Purves, A. Middlemas, +4 authors D. Tomlinson
- MedicineFASEB journal : official publication of the…
- 1 November 2001
The onset of diabetic neuropathy, a complication of diabetes mellitus, has been linked to poor glycemic control. We tested the hypothesis that the mitogen‐activated protein kinases (MAPK) form…
Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins.
- C. Abbott, M. Mackness, S. Kumar, A. Boulton, P. Durrington
- Chemistry, MedicineArteriosclerosis, thrombosis, and vascular…
- 1 November 1995
The results indicate that the low paraoxonase activity in diabetes is due to decreased specific activity and suggest an association with peripheral neuropathy, which could be due to reduced capacity to detoxify lipid peroxides in diabetes.