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Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea.
Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents).
- J. Calixto
- BiologyBrazilian journal of medical and biological…
- 1 February 2000
The trend in the domestication, production and biotechnological studies and genetic improvement of medicinal plants will offer great advantages, since it will be possible to obtain uniform and high quality raw materials which are fundamental to the efficacy and safety of herbal drugs.
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw
A review of the plants of the genus Phyllanthus: Their chemistry, pharmacology, and therapeutic potential
Together this data strongly supports the view that the plants belonging to the genus Phyllanthus have potential beneficial therapeutic actions in the management of hepatitis B, nefrolitiase, and in painful disorders.
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor
- F. Pamplona, J. Ferreira, R. N. Takahashi
- Biology, MedicineProceedings of the National Academy of Sciences
- 12 November 2012
It is shown that the anti-inflammatory lipid lipoxin A4 is an endogenous allosteric enhancer of the CB1 cannabinoid receptor, and displayed a CB1 receptor-dependent protective effect against β-amyloid (1–40)-induced spatial memory impairment in mice.
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
Kinins in pain and inflammation
Kinin B1 receptors: key G‐protein‐coupled receptors and their role in inflammatory and painful processes
- J. Calixto, R. Medeiros, E. Fernandes, J. Ferreira, D. Cabrini, M. Campos
- BiologyBritish journal of pharmacology
- 1 December 2004
The main advances achieved in the last 5 years about the participation of kinin B1 receptors in painful and inflammatory disorders are remarked and some groups of chronic diseases are pointed out, in which the strategic development of nonpeptidic oral‐available and selective B1 receptor antagonists could have a potential relevant therapeutic interest.
Involvement of NMDA receptors and l-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice