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etoposide phosphate

Known as: ETOP, etoposide phosphate [Chemical/Ingredient] 
A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (3)

Antineoplastic AgentsEtoposideOrganophosphorus Compounds

Narrower (3)

BMY-40481EtophosEtopophos
Bladder NeoplasmBrain NeoplasmsChronic Lymphocytic LeukemiaDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Characterizing the Active Opening of the Eustachian Tube in a Hypobaric/Hyperbaric Pressure Chamber
Objective Active and passive opening of the Eustachian tube (ET) enables direct aeration of the middle ear and a pressure balance… 
2009
2009
JS-K, an arylating nitric oxide (NO) donor, has synergistic anti-leukemic activity with cytarabine (ARA-C).
2004
2004
Quantification of etoposide and etoposide phosphate in human plasma by micellar electrokinetic chromatography and near-field thermal lens detection.
A method employing micellar electrokinetic chromatography in combination with near-field thermal lens detection (NF-TLD) was… 
Highly Cited
2002
Highly Cited
2002
Treatment of unresectable and metastatic hepatoblastoma: a pediatric oncology group phase II study.
PURPOSE To estimate the disease-response rate, proportion of patients whose tumors can be made resectable, event-free survival… 
2001
2001
Simultaneous quantification of etoposide and etoposide phosphate in human plasma by capillary electrophoresis using laser-induced native fluorescence detection.
A method using capillary electrophoresis with UV laser-induced native fluorescence detection was developed as a sensitive and… 
1999
1999
Successful Rechallenge with Etoposide Phosphate after an Acute Hypersensitivity Reaction to Etoposide
Hypersensitivity reactions to etoposide are reported infrequently and consist of hypotension, hypertension, flushing, diaphoresis… 
1998
1998
Separation of etoposide phosphate and methotrexate by capillary zone electrophoresis using UV detection with a high sensitivity cell
Etoposide phosphate and methotrexate are important anti‐tumor chemotherapeutic agents. Our previously presented capillary zone… 
1996
1996
Effects of gender, age, and race on the pharmacokinetics of etoposide after intravenous administration of etoposide phosphate in cancer patients.
The influence of gender, age, and race on the pharmacokinetics of etoposide and on the extent of conversion of etoposide… 
1995
1995
Phase I study of etoposide phosphate (etopophos) as a 30-minute infusion on days 1, 3, and 5.
Etoposide phophate is a phosphate ester prodrug of etoposide designed to improve the pharmaceutical characteristics of the parent… 
1995
1995
Pharmacokinetics and bioequivalence of etoposide following intravenous administration of etoposide phosphate and etoposide in patients with solid tumors.
PURPOSE To assess the pharmacokinetics and bioequivalence of etoposide following intravenous (i.v.) administration of etoposide… 
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