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etoposide phosphate

Known as: ETOP, etoposide phosphate [Chemical/Ingredient] 
A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Replication protein A (RPA) is a single-stranded DNA (ssDNA) binding protein involved in various processes, including nucleotide… 
Highly Cited
2004
Highly Cited
2004
PURPOSE P-glycoprotein (Pgp) is strongly inhibited by PSC-833. A chemotherapy dose-escalation study was performed with PSC-833 in… 
2004
2004
Apoptosis, or programmed cell death, is an orderly and genetically controlled form of cell death. In a morphological sense, it… 
Highly Cited
2002
Highly Cited
2002
In response to DNA damage, ataxia-telangiectasia mutant and ataxia-telangiectasia and Rad-3 activate p53, resulting in either… 
Highly Cited
2002
Highly Cited
2002
PURPOSE To estimate the disease-response rate, proportion of patients whose tumors can be made resectable, event-free survival… 
Review
1998
Review
1998
  • K. Hande
  • European journal of cancer
  • 1998
  • Corpus ID: 39068267
Highly Cited
1997
Highly Cited
1997
The mrp (multidrug resistance protein) gene has been associated with the multidrug resistance of cancer cells in vitro and in… 
Review
1996
Review
1996
The podophyllotoxin derivatives etoposide and teniposide are active in the treatment of a variety of malignant conditions. Both… 
Highly Cited
1988
Highly Cited
1988
Two anti-tumor monoclonal antibodies, L6 (anticarcinoma) and 1F5 (anti-B lymphoma), were covalently linked to alkaline…