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Chronic Lymphocytic Leukemia

Known as: Chronic B-Lymphocytic Leukemias, B-Cell Leukemias, Chronic, Lymphoma, CLL Lymphoplasmacytoid 
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and… 
National Institutes of Health

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2 ML Fludarabine phosphate 25 MG/ML InjectionAtypical lymphocyteB lymphoblastB-CELL MALIGNANCY, LOW-GRADE

Broader (1)

Chronic leukemia

Papers overview

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Highly Cited
2016
Highly Cited
2016
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.
BACKGROUND Irreversible inhibition of Bruton's tyrosine kinase (BTK) by ibrutinib represents an important therapeutic advance for… 
Highly Cited
2008
Highly Cited
2008
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
We conducted a genome-wide association study of 299,983 tagging SNPs for chronic lymphocytic leukemia (CLL) and performed… 
Highly Cited
2006
Highly Cited
2006
Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study.
BACKGROUND An increasing proportion of deaths among human immunodeficiency virus (HIV)-infected persons with access to… 
Highly Cited
2005
Highly Cited
2005
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia.
Activating mutations in tyrosine kinases have been identified in hematopoietic and nonhematopoietic malignancies. Recently, we… 
Highly Cited
2004
Highly Cited
2004
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia.
B cell chronic lymphocytic leukemia (CLL) is characterized by an accumulation of mature, functionally incompetent B cells. Wnts… 
Highly Cited
1993
Highly Cited
1993
bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia.
The bcl-2 gene becomes transcriptionally deregulated in the majority of low-grade non-Hodgkin lymphomas as a result of t(14;18… 
Highly Cited
1988
Highly Cited
1988
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.
The Philadelphia chromosome is present in more than 95% of chronic myeloid leukemia patients and 13% of acute lymphocytic… 
Highly Cited
1985
Highly Cited
1985
Nucleotide sequence of the AIDS virus, LAV
Highly Cited
1969
Highly Cited
1969
Modification of Parkinsonism--chronic treatment with L-dopa.
Abstract Slowly increasing oral doses of L-3,4-dihydroxyphenylalanine (L-dopa) induced at least partial improvement of some… 
Highly Cited
1966
Highly Cited
1966
SERUM AND URINARY LYSOZYME (MURAMIDASE) IN MONOCYTIC AND MONOMYELOCYTIC LEUKEMIA
Markedly increased quantities of lysozyme have been found in the serum and urine (ranging to 2.6 g per day) of ten consecutive… 
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