Chronic Lymphocytic Leukemia

Known as: Chronic B-Lymphocytic Leukemias, B-Cell Leukemias, Chronic, Lymphoma, CLL Lymphoplasmacytoid 
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and… (More)

Topic mentions per year

Topic mentions per year

1936-2017
05001000150019362016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
BACKGROUND The treatment of relapsed chronic lymphocytic leukemia (CLL) has resulted in few durable remissions. Bruton's tyrosine… (More)
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Highly Cited
2013
Highly Cited
2013
Clonal evolution is a key feature of cancer progression and relapse. We studied intratumoral heterogeneity in 149 chronic… (More)
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Highly Cited
2011
Highly Cited
2011
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with… (More)
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Highly Cited
2008
Highly Cited
2008
Standardized criteria for diagnosis and response assessment are needed to interpret and compare clinical trials and for approval… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND MicroRNA expression profiles can be used to distinguish normal B cells from malignant B cells in patients with chronic… (More)
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Highly Cited
2004
Highly Cited
2004
Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal and neoplastic cells, although it is… (More)
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Highly Cited
2002
Highly Cited
2002
Micro-RNAs (miR genes) are a large family of highly conserved noncoding genes thought to be involved in temporal and tissue… (More)
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Highly Cited
1999
Highly Cited
1999
Cellular immunophenotypic studies were performed on a cohort of randomly selected IgM(+) B-chronic lymphocytic leukemia (B-CLL… (More)
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Highly Cited
1999
Highly Cited
1999
Despite having several characteristics of naïve B cells, chronic lymphocytic leukemia (CLL) cells have been shown in some cases… (More)
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Highly Cited
1975
Highly Cited
1975
A method of clinical staging of chronic lymphocytic leukemia (CLL) has been proposed which is based on the concept that CLL is a… (More)
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