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Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection
Background In the Strategies for Management of Anti-Retroviral Therapy trial, all-cause mortality was higher for participants randomized to intermittent, CD4-guided antiretroviral treatment (ART)Expand
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Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection.
BACKGROUND Data from randomized trials are lacking on the benefits and risks of initiating antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) infection who have aExpand
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CD4+ count-guided interruption of antiretroviral treatment.
BACKGROUND Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance ofExpand
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Class of antiretroviral drugs and the risk of myocardial infarction.
BACKGROUND We have previously demonstrated an association between combination antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this association differs accordingExpand
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Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study.
BACKGROUND An increasing proportion of deaths among human immunodeficiency virus (HIV)-infected persons with access to combination antiretroviral therapy (cART) are due to complications of liverExpand
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Combination antiretroviral therapy and the risk of myocardial infarction.
BACKGROUND It remains controversial whether exposure to combination antiretroviral treatment increases the risk of myocardial infarction. METHODS In this prospective observational study, weExpand
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Remdesivir for the Treatment of Covid-19 — Preliminary Report
Abstract Background Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), none have yet been shown to be efficacious. Methods We conductedExpand
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Cardiovascular disease risk factors in HIV patients – association with antiretroviral therapy. Results from the DAD study
Objective: To determine the prevalence of risk factors for cardiovascular disease (CVD) among HIV-infected persons, and to investigate any association between such risk factors, stage of HIV disease,Expand
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Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy.
IMPORTANCE A key factor in assessing the effectiveness and cost-effectiveness of antiretroviral therapy (ART) as a prevention strategy is the absolute risk of HIV transmission through condomless sexExpand
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Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients
Objectives:Chronic kidney disease (CKD) in HIV-positive persons might be caused by both HIV and traditional or non-HIV-related factors. Our objective was to investigate long-term exposure to specificExpand
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