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dotarizine

Known as: 1-(diphenylmethyl)-4-(3-(2-phenyl-1,3-dioxalen-2-yl)propyl)piperazine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (5)

Benzhydryl CompoundsCalcium Channel BlockersPiperazinesSerotonin Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells.
1999
1999
Novel antimigraineur dotarizine releases Ca2+ from caffeine‐sensitive Ca2+ stores of chromaffin cells
The novel antimigraineur, dotarizine (30 μM), increased cytosolic Ca2+ concentration, [Ca2+]c, in fura‐2‐loaded bovine adrenal… 
1999
1999
Influence of inhibitors on increase in intracellular free calcium and proliferation induced by platelet-activating factor in bovine oviductal cells.
Oviductal endosalpingeal cells were isolated mechanically from heifers and cultured until there was 100% confluency. The cells… 
1998
1998
[Efficacy and safety of dotarizine vs. cinnarizine in the symptomatic treatment of acute balance disorders (common vertigo)].
One hundred and ten adult patients suffering from peripheral vertigo were treated in a multifactorial double-blind randomized… 
1997
1997
'Wide-spectrum Ca2+ channel antagonists': lipophilicity, inhibition, and recovery of secretion in chromaffin cells.
1997
1997
Serotonergic effects of dotarizine in coronary artery and in oocytes expressing 5-HT2 receptors.
1995
1995
Dotarizine versus flunarizine as calcium antagonists in chromaffin cells
1 Dotarizine is a novel piperazine derivative structurally related to flunarizine that is currently being evaluated in clinical… 
1995
1995
Anxiolytic effects of dotarizine, a possible antimigraine drug.
In experiments on rats in elevated plus-maze and in Opto Varimex apparatus, used for studying exploratory behavior, we observed… 
1994
1994
Effects of dotarizine on peripheral and pulmonary circulation and cardiac dynamics in dogs.
The cardiovascular effects of dotarizine in 10-min intravenous infusions were studied in thiopental-anesthetized dogs. The… 
1993
1993
Effects of dotarizine on 45Ca2+ movements and contractile responses in vascular smooth muscle.
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