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cytochrome P450 3A4 protein, human

Known as: Cytochrome P450 HLp, P450, FAMILY III, EC 1.14.13.67 
Cytochrome P450 3A4 (503 aa, ~57 kDa) is encoded by the human CYP3A4 gene. This protein is involved in the oxidation of steroids, fatty acids and… 
National Institutes of Health

Related topics

Related topics

50 relations
Alfentanil hydrochlorideBetamethasone benzoateCarbamazepineCortisone

Broader (3)

Cytochrome P-450 CYP3A4Cytochrome P450cytochrome P450 3A

Papers overview

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2013
2013
Evaluation of Luminescent P 450 Analysis for Directed Evolution of Human CYP 4 A 11
Cytochrome P450s (CYPs, P450s) comprise the superfamily of heme-containing oxidoreductase enzymes found in various organisms… 
2006
2006
Cytochrome P-450 3 A 4 ( Nifedipine Oxidase ) Is Responsible for the C-oxidative Metabolism of 1-Nitropyrene in Human Liver Microsomal Samples 1
The nitrated polycyclic aromatic hydrocarbon 1-nitropyrene is a ubiq uitous environmental pollutant. The role of cytochromes P… 
2004
2004
Effects of seal oil on the correlation between hepatocyte cytochrome P450 2E1 expression and oxidation, antioxidation in rats with nonalcoholic fatty liver
AIM: To explore the effects of seal oil on the correlation between hepatocyte cytochrome P450 2E1 expression and oxidation… 
2004
2004
Omega-hydroxylation of phytanic acid in rat liver microsomes: implications for Refsum disease.
The 3-methyl-branched fatty acid phytanic acid is degraded by the peroxisomal alpha-oxidation route because the 3-methyl group… 
1985
1985
Role of superoxide in the N-oxidation of N-(2-methyl-1-phenyl-2-propyl)hydroxylamine by the rat liver cytochrome P-450 system.
The N-oxidation of N-(2-methyl-1-phenyl-2-propyl)hydroxylamine (N-hydroxyphentermine, MPPNHOH) and the N-hydroxylation of 2… 
1985
1985
Oxidation of arylcyclopropanes by rabbit liver cytochrome P-450. Mechanistic implications of a multiple oxidation.
The arylcyclopropanes (cyclopropylarenes) cyclopropylbenzene and diphenylcyclopropane are oxidized by rabbit liver microsomal… 
1985
1985
[Stoichiometry of microsomal oxidation reactions. Distribution of redox-equivalents in monooxygenase and oxidase reactions catalyzed by cytochrome P-450].
The stoichiometry of NADPH oxidation in rabbit liver microsomes was studied. It was shown that in uncoupled reactions cytochrome… 
1984
1984
Drug metabolism in diabetic subjects with fatty livers.
The effect of fatty degeneration of liver parenchyma on drug metabolism was investigated in 21 obese non-insulin-dependent… 
1980
1980
Enzymatic mono oxygenation of halogen atoms cytochrome p 450 catalyzed oxidation of iodo benzene by iodoso benzene
1969
1969
Cytochrome P-450 in the omega-oxidation of fatty acids.