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Cytochrome P450

Known as: Cytochrome-P450, Superfamily, Cytochrome P450, cytochrome P450 enzyme system 
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The Power Behind P450 Drugs, toxins and a range of metabolic substrates are detoxified in the liver by family of iron-containing… Expand
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Highly Cited
2009
Highly Cited
2009
The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 (CYP) genes… Expand
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Review
2009
Review
2009
Pharmacogenetics is the study of how interindividual variations in the DNA sequence of specific genes affect drug response. This… Expand
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Review
2008
Review
2008
The field of cytochrome P450 (P450) research has developed considerably over the past 20 years, and many important papers on the… Expand
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Review
2006
Review
2006
Some cytochrome P450 (CYP) heme-thiolate enzymes participate in the detoxication and, paradoxically, the formation of reactive… Expand
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Review
2005
Review
2005
CYP2D6 is of great importance for the metabolism of clinically used drugs and about 20–25% of those are metabolised by this… Expand
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Review
2001
Review
2001
Cytochrome P450 (P450) enzymes catalyze a variety of reactions and convert chemicals to potentially reactive products as well as… Expand
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Review
1998
Review
1998
The cytochrome P450s (CYPs) constitute a superfamily of isoforms that play an important role in the oxidative metabolism of drugs… Expand
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Highly Cited
1996
Highly Cited
1996
The cpd mutation localized by T-DNA tagging on Arabidopsis chromosome 5-14.3 inhibits cell elongation controlled by the ecdysone… Expand
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Highly Cited
1991
Highly Cited
1991
ion, the intermediates themselves may arrange to influence the course of the reaction to products. Groves showed that in allylic… Expand
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