Cytochrome P450

Known as: Cytochrome-P450, Superfamily, Cytochrome P450, cytochrome P450 enzyme system 
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1939-2018
050019392017

Papers overview

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Highly Cited
2009
Highly Cited
2009
The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 (CYP) genes… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Both clopidogrel and prasugrel require biotransformation to active metabolites by cytochrome P450 (CYP) enzymes. Among… (More)
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Highly Cited
2009
Highly Cited
2009
Cytochrome P450 (P450) enzymes are important in the metabolism of steroids, vitamins, carcinogens, drugs and other compounds. Two… (More)
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Highly Cited
2006
Highly Cited
2006
The capacity of clopidogrel to inhibit ADP-induced platelet aggregation shows wide intersubject variability. To determine whether… (More)
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Highly Cited
2006
Highly Cited
2006
Cytochrome P450 (CYP) 3A4 is the most promiscuous of the human CYP enzymes and contributes to the metabolism of approximately 50… (More)
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Highly Cited
2006
Highly Cited
2006
MicroRNAs (miRNA) are small noncoding RNAs that regulate gene expression through translational repression or mRNA cleavage. Here… (More)
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Highly Cited
2004
Highly Cited
2004
The hormonal action of abscisic acid (ABA) in plants is controlled by the precise balance between its biosynthesis and catabolism… (More)
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
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Highly Cited
1997
Highly Cited
1997
Cytochrome P450 CYP1B1 is a recently cloned dioxin-inducible form of the cytochrome P450 family of xenobiotic metabolizing… (More)
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Highly Cited
1996
Highly Cited
1996
The cpd mutation localized by T-DNA tagging on Arabidopsis chromosome 5-14.3 inhibits cell elongation controlled by the ecdysone… (More)
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