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Cytochrome P450

Known as: Cytochrome-P450, Superfamily, Cytochrome P450, cytochrome P450 enzyme system 
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The Power Behind P450 Drugs, toxins and a range of metabolic substrates are detoxified in the liver by family of iron-containing… 
Highly Cited
2009
Highly Cited
2009
  • D. Nelson
  • Human Genomics
  • 2009
  • Corpus ID: 24052788
The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 (CYP) genes… 
Review
2008
Review
2008
  • F. Guengerich
  • Chemical research in toxicology
  • 2008
  • Corpus ID: 17548932
The field of cytochrome P450 (P450) research has developed considerably over the past 20 years, and many important papers on the… 
Review
2005
Review
2005
CYP2D6 is of great importance for the metabolism of clinically used drugs and about 20–25% of those are metabolised by this… 
Review
2004
Review
2004
ion phase that leads to an alkyl radical coordinated to the iron-hydroxo complex by a weak OH---C hydrogen bond, labeled as CI… 
Review
2001
Review
2001
  • F. Guengerich
  • Chemical research in toxicology
  • 2001
  • Corpus ID: 32038435
Cytochrome P450 (P450) enzymes catalyze a variety of reactions and convert chemicals to potentially reactive products as well as… 
Review
1998
Review
1998
The cytochrome P450s (CYPs) constitute a superfamily of isoforms that play an important role in the oxidative metabolism of drugs… 
Highly Cited
1993
Highly Cited
1993
ion, the intermediates themselves may arrange to influence the course of the reaction to products. Groves showed that in allylic… 
Review
1992
Review
1992
The cytochromes P450 are a superfamily of hemoproteins that catalyze the metabolism of a large number of xenobiotics and…