Aldosterone Synthase

Known as: Steroid 18 Hydroxylase, Cytochrome P-450 CYP11B2, Aldosterone Synthase Cytochrome P-450 
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
05101519892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
An increase in plasma ANG II causes neuronal activation in hypothalamic nuclei and a slow pressor response, presumably by… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
2010
2010
Aldosterone synthesis is regulated by angiotensin II (Ang II) and K(+) acting in the adrenal zona glomerulosa, in part through… (More)
Is this relevant?
2006
2006
OBJECTIVES We sought to evaluate the effect of the aldosterone synthase promoter polymorphism on heart failure outcomes for… (More)
Is this relevant?
2003
2003
We have developed a highly sensitive QRT-PCR method for the measurement of CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
2002
2002
Aldosterone synthase (CYP11B2) is expressed in the adrenal glomerulosa and controls the capacity of the adrenal glomerulosa to… (More)
Is this relevant?
2002
2002
BACKGROUND The presence and pathophysiological role of CYP11B1 (11beta-hydroxylase) gene in the zona glomerulosa of human adrenal… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Anomalies in either of the tightly linked genes encoding the enzymes CYP11B1 (11beta-hydroxylase) or CYP11B2 (aldosterone… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?
1998
1998
The renin-angiotensin-aldosterone system plays an important role in large artery structure and blood pressure homeostasis. Among… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
NCI-H295 is a recently described human adrenocortical carcinoma cell line that makes a variety of steroid hormones. We sought to… (More)
Is this relevant?
1992
1992
Glucocorticoid-suppressible hyperaldosteronism (GSH) is an autosomal dominant form of familial hypertension. The biochemical… (More)
Is this relevant?