coumarin

Known as: alpha benzopyrone, cumarin, 2H-1-Benzopyran-2-one 
A substance used to make drugs that prevent and treat blood clots in blood vessels and treat certain heart conditions. Coumarin is taken from certain… (More)

Topic mentions per year

Topic mentions per year

1936-2017
020040019362016

Papers overview

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Highly Cited
2005
Highly Cited
2005
PURPOSE Experimental studies and indirect clinical evidence suggest that low molecular weight heparins may have antineoplastic… (More)
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Highly Cited
2005
Highly Cited
2005
The NAD+-dependent protein deacetylase family, Sir2 (or sirtuins), is important for many cellular processes including gene… (More)
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Highly Cited
2004
Highly Cited
2004
Coumarin derivatives such as warfarin represent the therapy of choice for the long-term treatment and prevention of… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Patients with cancer have a substantial risk of recurrent thrombosis despite the use of oral anticoagulant therapy. We… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Heat shock protein 90 (Hsp90) interacts with and stabilizes several oncogenic protein kinases (e.g., p185(erbB2), p60… (More)
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Highly Cited
1998
Highly Cited
1998
We examined the expression, activation, and cellular localization of caspase-3 (CPP32) using immunohistochemistry, immunoblots… (More)
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Highly Cited
1997
Highly Cited
1997
Nine organic solvents and 47 commonly used P450 substrates and inhibitors were examined for their effects on coumarin 7… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Bleeding is the most serious complication of the use of oral anticoagulation in the prevention and treatment of… (More)
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Highly Cited
1992
Highly Cited
1992
(7-methoxycoumarin-4-yl)Acetyl-Pro-Leu-Gly-Leu-(3-[2,4-dinitrophenyl]-L- 2,3-diaminopropionyl)-Ala-Arg-NH2 (Mca-Pro-Leu-Gly-Leu… (More)
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Highly Cited
1990
Highly Cited
1990
Three cDNAs, designated IIA3, IIA3v, and IIA4, coding for P450s in the CYP2A gene subfamily were isolated from a lambda gt11… (More)
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