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coumarin

Known as: 1,2-Benzopyrone, Tonka bean camphor, alpha benzopyrone 
A substance used to make drugs that prevent and treat blood clots in blood vessels and treat certain heart conditions. Coumarin is taken from certain… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (3)

4-hydroxycoumarinFurocoumarinsWarfarin
ALCOHOL 75 mL in 100 mL TOPICAL LIQUID [Game Day MSC Mainstreet Collection Hand Sanitizer]ALUMINUM CHLOROHYDRATE 0.25 g in 1 mL TOPICAL AEROSOL [Mitchum Advance Control Powder Fresh]ALUMINUM CHLOROHYDRATE 12.3 g in 12.3 mL TOPICAL STICK [Vesen Antiperpirant Deodorant Roll-On JAFRA]ALUMINUM ZIRCONIUM OCTACHLOROHYDREX GLY 0.2 g in 1 mL TOPICAL LIQUID [Revlon Mitchum Clinical Gel]

Broader (3)

BenzopyransCoumarinsPyrones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Coumarin heterocyclic derivatives: chemical synthesis and biological activity.
This review highlights the broad range of science that has arisen from the synthesis of coumarin-linked and fused heterocycle… 
Review
2010
Review
2010
Coumarins: old compounds with novel promising therapeutic perspectives.
Natural as well as synthetic coumarins have recently drawn much attention due to its broad pharmacological activities. Many… 
Review
2008
Review
2008
A review of coumarin derivatives in pharmacotherapy of breast cancer.
The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in natural products (such as the anticoagulant warfarin… 
Highly Cited
2007
Highly Cited
2007
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.
Structures of human monoamine oxidase B (MAO B) in complex with safinamide and two coumarin derivatives, all sharing a common… 
Highly Cited
2007
Highly Cited
2007
Fluorescence turn on of coumarin derivatives by metal cations: a new signaling mechanism based on C=N isomerization.
[reaction: see text] A new sensing mechanism based on C=N isomerization, which shows a very significant fluorescence enhancement… 
Highly Cited
2005
Highly Cited
2005
Synthesis and antiinflammatory activity of coumarin derivatives.
The synthesis of several coumarin Mannich bases is described. The structures of the synthesized compounds were confirmed by… 
Highly Cited
2005
Highly Cited
2005
Antioxidant activity of citrus limonoids, flavonoids, and coumarins.
A variety of in vitro models such as beta-carotene-linoleic acid, 1,1-diphenyl-2-picryl hydrazyl (DPPH), superoxide, and hamster… 
Highly Cited
2003
Highly Cited
2003
Biological Evaluation of Several Coumarin Derivatives Designed as Possible Anti-inflammatory/Antioxidant Agents
Several linear and angular coumarins designed and synthesised as possible anti-inflammatory and antioxidant agents were evaluated… 
Highly Cited
1993
Highly Cited
1993
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs.
We have cloned and overexpressed a gene encoding a 43-kDa protein corresponding to the N-terminal fragment of the DNA gyrase B… 
Review
1993
Review
1993
The interaction between coumarin drugs and DNA gyrase
The coumarin group of antibiotics have as their target the bacterial enzyme DNA gyrase. The drugs bind to the B subunit of gyrase… 
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