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Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer.
We have previously demonstrated that a clinical model can be safely used in a management strategy in patients with suspected pulmonary embolism (PE). We sought to simplify the clinical model and… Expand
Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature.
BACKGROUND The management of women with prosthetic heart valves during pregnancy poses a particular challenge as there are no available controlled clinical trials to provide guidelines for effective… Expand
Use of a Clinical Model for Safe Management of Patients with Suspected Pulmonary Embolism
- P. Wells, Jeffrey S. Ginsberg, +9 authors J. Hirsh
- Annals of Internal Medicine
- 15 December 1998
Because the signs and symptoms of pulmonary embolism are nonspecific, objective diagnostic tests are warranted when this event is suspected [1, 2]. Many algorithms have been suggested for the… Expand
A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism.
BACKGROUND Patients who have a first episode of venous thromboembolism in the absence of known risk factors for thrombosis (idiopathic thrombosis) are often treated with anticoagulant therapy for… Expand
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery.
Dabigatran, an oral once-daily unmonitored thrombin inhibitor, has been tested elsewhere using enoxaparin 40 mg once daily. We used the North American enoxaparin 30 mg BID regimen as the comparator.… Expand
Use of antithrombotic agents during pregnancy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
This chapter about the use of antithrombotic agents during pregnancy is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1… Expand
Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism.
- C. Kearon, Jeffrey S. Ginsberg, +17 authors M. Gent
- The New England journal of medicine
- 14 August 2003
BACKGROUND Warfarin is very effective in preventing recurrent venous thromboembolism but is also associated with a substantial risk of bleeding. After three months of conventional warfarin therapy, a… Expand
Use of antithrombotic agents during pregnancy.
Anticoagulant therapy is indicated during pregnancy for the prevention and treatment of venous thromboembolism and for the prevention and treatment of systemic embolism in patients with prosthetic… Expand
Relationship between deep venous thrombosis and the postthrombotic syndrome.
The postthrombotic syndrome (PTS) is a frequent complication of deep venous thrombosis (DVT). Clinically, PTS is characterized by chronic, persistent pain, swelling, and other signs in the affected… Expand
Noninvasive diagnosis of deep venous thrombosis. McMaster Diagnostic Imaging Practice Guidelines Initiative.
PURPOSE To review noninvasive methods for diagnosis of first and recurrent deep venous thrombosis and provide evidence-based recommendations for the diagnosis of deep venous thrombosis in… Expand