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Warfarin

Known as: 3-Alpha-phenyl-beta-acetylethyl-4-hydroxycoumarin, 3-(.alpha.-Phenyl-.beta.-acetylethyl)-4-hydroxycoumarin, 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)- 
A synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Numerous vascular risk factors and vascular diseases contribute to cognitive impairment and dementia. Many studies and registries… Expand
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Review
2017
Review
2017
1. Euthanasia. Amsterdam: Government of the Netherlands (https:/ / www .government .nl/ topics/ euthanasia). 2. Quill TE. Legal… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Vitamin K antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases the risk of hemorrhage and is… Expand
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Highly Cited
2009
Highly Cited
2009
To the Editor: Although Connolly et al. (Sept. 17 issue)1 have demonstrated a modest advantage for dabigatran over warfarin in… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The direct oral thrombin inhibitor dabigatran has a predictable anticoagulant effect and may be an alternative therapy… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Genetic variability among patients plays an important role in determining the dose of warfarin that should be used… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The management of warfarin therapy is complicated by a wide variation among patients in drug response. Variants in the… Expand
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