Skip to search formSkip to main contentSkip to account menu

Warfarin

Known as: 3-Alpha-phenyl-beta-acetylethyl-4-hydroxycoumarin, 3-(.alpha.-Phenyl-.beta.-acetylethyl)-4-hydroxycoumarin, 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)- 
A synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (14)

10-hydroxywarfarin3'-hydroxywarfarin4'-hydroxywarfarin7-hydroxywarfarin
Alcoholic Intoxication, ChronicAtrial FibrillationCYP1A2 protein, humanCYP2C19 protein, human

Broader (2)

AnticoagulantsRodenticides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study
Highly Cited
2016
Highly Cited
2016
Effectiveness and Safety of Dabigatran, Rivaroxaban, and Apixaban Versus Warfarin in Nonvalvular Atrial Fibrillation
Background The introduction of non–vitamin K antagonist oral anticoagulants has been a major advance for stroke prevention in… 
Highly Cited
2009
Highly Cited
2009
The largest prospective warfarin-treated cohort supports genetic forecasting.
Genetic variants of cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) are known to influence warfarin dose… 
Highly Cited
2009
Highly Cited
2009
Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation.
Use of warfarin, clopidogrel, or aspirin associates with mortality among patients with ESRD, but the risk-benefit ratio may… 
Review
2008
Review
2008
Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues
Using pharmacogenetics-based therapy, clinicians can estimate the therapeutic warfarin dose by genotyping patients for single… 
Highly Cited
2005
Highly Cited
2005
Common VKORC1 and GGCX polymorphisms associated with warfarin dose
We report a novel combination of factors that explains almost 60% of variable response to warfarin. Warfarin is a widely used… 
Review
2004
Review
2004
Advanced Age, Anticoagulation Intensity, and Risk for Intracranial Hemorrhage among Patients Taking Warfarin for Atrial Fibrillation
Context The appropriate level of warfarin anticoagulation in elderly patients with atrial fibrillation has been debated because… 
Highly Cited
2003
Highly Cited
2003
Relationship Between Patients’ Warfarin Knowledge and Anticoagulation Control
OBJECTIVE To evaluate patients’ knowledge of warfarin and its relationship to anticoagulation control. METHODS From January to… 
Highly Cited
2002
Highly Cited
2002
Warfarin, aspirin, or both after myocardial infarction.
BACKGROUND The role of antithrombotic therapy in secondary prevention after myocardial infarction is well established. Although… 
Highly Cited
2001
Highly Cited
2001
Crystal Structure Analysis of Warfarin Binding to Human Serum Albumin
Human serum albumin (HSA) is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)