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7-hydroxywarfarin

Known as: 2H-1-Benzopyran-2-one, 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)- 
National Institutes of Health

Papers overview

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Highly Cited
2010
2010
2010
Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation… 
2008
2008
Chimeric mice having humanized livers were constructed by transplantation of human hepatocytes. In this study, we investigated… 
1999
1999
To clarify the mechanism(s) for the interaction between warfarin and benzbromarone, a uricosuric agent, and to predict changes in… 
Review
1997
Review
1997
Highly Cited
1997
Highly Cited
1997
Cytochrome P4502C9 (CYP2C9) is largely responsible for terminating the anticoagulant effect of racemic warfarin via hydroxylation… 
Highly Cited
1978
Highly Cited
1978
Highly Cited
1976
Highly Cited
1976
Highly Cited
1974
Highly Cited
1974
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by…