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7-hydroxywarfarin

Known as: 2H-1-Benzopyran-2-one, 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)- 
National Institutes of Health

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2 relations

Broader (1)

Warfarin
analogs & derivatives

Papers overview

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2015
2015
Analytical aspects of achiral and cyclodextrin-mediated capillary electrophoresis of warfarin and its two main derivatives assisted by theoretical modeling.
2014
2014
Fast separation of warfarin and 7-hydroxywarfarin enantiomers by cyclodextrin-assisted capillary electrophoresis.
The enantioseparation of warfarin and its main metabolite has been achieved using several cyclodextrin types and buffers at… 
2008
2008
Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
Recent studies show that the extrahepatic human UDP-glucuronosyltransferase (UGT)1A10 is capable of phase II glucuronidation of… 
1993
1993
Warfarin metabolites: stereochemical aspects of protein binding and displacement by phenylbutazone.
The in vitro human serum albumin binding characteristics of the enantiomers of the major metabolites of warfarin [6… 
1993
1993
Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)‐warfarin is not enhanced in cystic fibrosis
Enhanced metabolism of theophylline in subjects with cystic fibrosis suggests that the activity of certain cytochrome P450… 
1991
1991
Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes.
Highly Cited
1984
Highly Cited
1984
Stereospecific fluorescence high-performance liquid chromatographic analysis of warfarin and its metabolites in plasma and urine.
A stereospecific assay for the simultaneous determination of the enantiomers of warfarin and its major metabolites, 6- and 7… 
1981
1981
Changes in the metabolic profiles of R- and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases.
1977
1977
Biliary excretion of warfarin metabolites and their metabolism by rat gut flora.
1975
1975
Studies of the microsomal drug metabolism system in warfarin-resistant and -susceptible rats.
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