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Direct-injection LC-MS-MS method for high-throughput simultaneous quantitation of simvastatin and simvastatin acid in human plasma.
A direct-injection liquid chromatography-mass spectrometry-mass spectrometry (LC-MS-MS) method was developed and validated for the simultaneous quantitation in human plasma of the widely usedExpand
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Percentage of cells in the S phase of the cell cycle in human lymphoma determined by flow cytometry.
The percentage of cells with S phase DNA content (S cells) was determined by flow cytometry in cell suspensions obtained from 27 patients with non-Hodgkin's lymphomas. DNA was measured inExpand
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Virus infection as a stressor: Influenza virus elevates plasma concentrations of corticosterone, and brain concentrations of MHPG and tryptophan
Balb/c mice were infected with influenza virus PR8 (H1N1) by the intranasal route. At various subsequent times, brain samples were examined for their content of catecholamine and indoleamineExpand
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Effects of Newcastle disease virus administration to mice on the metabolism of cerebral biogenic amines, plasma corticosterone, and lymphocyte proliferation
Newcastle disease virus (NDV) administration to mice increased concentrations of plasma corticosterone, with a maximal effect at 8 h. This elevation of plasma corticosterone concentrations was notExpand
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A Rights-Based Approach to Gender Equality and Women's Rights
ABSTRACT In the face of continuing gender inequalities and violations of women's rights, questions are being asked as to whether the predominant approach used by donor organizations—genderExpand
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Quantitative selected ion monitoring (QSIM) of drugs and/or drug metabolites in biological matrices.
From a modest beginning, QSIM has established itself with over three hundred applications in the 1970s as not only a reference technique for other methods but also as a useful method in its own rightExpand
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Virus-induced increases in plasma corticosterone.
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Relationship between systemic drug absorption and gastrointestinal transit after the simultaneous oral administration of carbamazepine as a controlled-release system and as a suspension of
1. Plasma drug concentrations after a single oral administration of a suspension of carbamazepine (CBZ) and a 20/200 CBZ Oros osmotic pump system were measured in eight healthy male volunteers. TheExpand
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Increased throughput in quantitative bioanalysis using parallel-column liquid chromatography with mass spectrometric detection.
The feasibility of quantitative bioanalysis by parallel-column liquid chromatography in conjunction with a conventional single-source electrospray mass spectrometer has been investigated using plasmaExpand
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An automated method of sample preparation of biofluids using pierceable caps to eliminate the uncapping of the sample tubes during sample transfer.
Biological samples are normally collected and stored frozen in capped tubes until analysis. To obtain aliquots of biological samples for analysis, the sample tubes have to be thawed, uncapped,Expand
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