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- Publications
- Influence
Human malaria parasites in continuous culture.
- W. Trager, J. B. Jensen
- Biology, Medicine
- Science
- 20 August 1976
Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon… Expand
Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum.
Three clones have been prepared from the Honduras I/CDC strain of Plasmodium falciparum by a method of microscopic selection. One of these (HB-2) does not form gametocytes whereas the others (HB-1… Expand
THE CULTIVATION OF A CELLULOSE-DIGESTING FLAGELLATE, TRICHOMONAS TERMOPSIDIS, AND OF CERTAIN OTHER TERMITE PROTOZOA
- W. Trager
- Biology
- 1 April 1934
By means of preliminary experiments, the osmotic pressure, pH, and mono- to bivalent ion ratio most favorable to the survival of the symbiotic intestinal flagellates of termites were determined. On… Expand
Fine structure of human malaria in vitro.
- S. G. Langreth, J. B. Jensen, Robert T. Reese, W. Trager
- Biology, Medicine
- The Journal of protozoology
- 1 November 1978
The erythrocytic cycle of the human malaria parasite, Plasmodium, falciparum, was examined by electron microscopy. Three strains of parasites maintained in continuous culture in human erythrocytes… Expand
Cultivation of malarial parasites
- W. Trager, James B. Jenson
- Biology, Medicine
- Nature
- 22 June 1978
The method for continuous cultivation of Plasmodium falciparum has now been successfully applied to several strains from different geographical areas. It has been used for tests of antimalarial… Expand
In vitro evaluation of potential drug interactions with levetiracetam, a new antiepileptic agent.
- J. Nicolás, P. Collart, +4 authors J. Roba
- Chemistry, Medicine
- Drug metabolism and disposition: the biological…
- 1 February 1999
Levetiracetam and its carboxylic metabolite (AcL) were tested for their potential inhibitory effect on 11 different drug metabolizing enzyme activities using human liver microsomes. The following… Expand
Human Malaria Parasites in Continuous Culture
- W. Trager, J. B. Jensen
- Biology
- 1 June 2005
Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38°C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and… Expand
Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method.
- J. B. Jensen, W. Trager
- Biology, Medicine
- The Journal of parasitology
- 1 October 1977
Plasmodium falciparum has been cultured continuously in a simplified technique using plastic petri dishes in a candle jar. This method has the advantage of being readily adaptable to many… Expand
A New Virus of Ducks Interfering with Development of Malaria Parasite (Plasmodium lophurae).
- W. Trager
- Biology, Medicine
- Proceedings of the Society for Experimental…
- 1 July 1959
Summary In the course of passage of P. lophurae in ducklings by weekly transfer of infected blood, a contaminating infective agent appeared which inhibited malarial infection and caused rapid death… Expand
Plasmodium falciparum: enhanced gametocyte formation in vitro in reticulocyte-rich blood.
- W. Trager, G. Gill, C. Lawrence, R. L. Nagel
- Biology, Medicine
- Experimental parasitology
- 1 February 1999
Concentrates of late stage parasites of the gametocyte-forming clone HB-3 were mixed with blood rich in reticulocytes from anemic patients, or with normal control blood, and kept under culture… Expand