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Human malaria parasites in continuous culture.
Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbonExpand
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Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum.
  • V. Bhasin, W. Trager
  • Biology, Medicine
  • The American journal of tropical medicine and…
  • 6 September 1983
Three clones have been prepared from the Honduras I/CDC strain of Plasmodium falciparum by a method of microscopic selection. One of these (HB-2) does not form gametocytes whereas the others (HB-1Expand
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THE CULTIVATION OF A CELLULOSE-DIGESTING FLAGELLATE, TRICHOMONAS TERMOPSIDIS, AND OF CERTAIN OTHER TERMITE PROTOZOA
By means of preliminary experiments, the osmotic pressure, pH, and mono- to bivalent ion ratio most favorable to the survival of the symbiotic intestinal flagellates of termites were determined. OnExpand
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Fine structure of human malaria in vitro.
The erythrocytic cycle of the human malaria parasite, Plasmodium, falciparum, was examined by electron microscopy. Three strains of parasites maintained in continuous culture in human erythrocytesExpand
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Cultivation of malarial parasites
The method for continuous cultivation of Plasmodium falciparum has now been successfully applied to several strains from different geographical areas. It has been used for tests of antimalarialExpand
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In vitro evaluation of potential drug interactions with levetiracetam, a new antiepileptic agent.
Levetiracetam and its carboxylic metabolite (AcL) were tested for their potential inhibitory effect on 11 different drug metabolizing enzyme activities using human liver microsomes. The followingExpand
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Human Malaria Parasites in Continuous Culture
Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38°C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide andExpand
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Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method.
Plasmodium falciparum has been cultured continuously in a simplified technique using plastic petri dishes in a candle jar. This method has the advantage of being readily adaptable to manyExpand
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A New Virus of Ducks Interfering with Development of Malaria Parasite (Plasmodium lophurae).
  • W. Trager
  • Biology, Medicine
  • Proceedings of the Society for Experimental…
  • 1 July 1959
Summary In the course of passage of P. lophurae in ducklings by weekly transfer of infected blood, a contaminating infective agent appeared which inhibited malarial infection and caused rapid deathExpand
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Plasmodium falciparum: enhanced gametocyte formation in vitro in reticulocyte-rich blood.
Concentrates of late stage parasites of the gametocyte-forming clone HB-3 were mixed with blood rich in reticulocytes from anemic patients, or with normal control blood, and kept under cultureExpand
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