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10-hydroxywarfarin

Known as: 4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one 
National Institutes of Health

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2 relations

Broader (1)

Warfarin
analogs & derivatives

Papers overview

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2018
2018
Combination index of the concentration and in vivo antagonism activity of racemic warfarin and its metabolites to assess individual drug responses
The present study was undertaken to examine whether in vivo vitamin K epoxide reductase complex 1 (VKOR) “actual” antagonism… 
2016
2016
Cyclodextrin-assisted enantioseparation of warfarin and 10-hydroxywarfarin by capillary electrophoresis studied from the analytical and thermodynamic points of view.
2015
2015
Analytical aspects of achiral and cyclodextrin-mediated capillary electrophoresis of warfarin and its two main derivatives assisted by theoretical modeling.
2008
2008
Glucuronidation of Monohydroxylated Warfarin Metabolites by Human Liver Microsomes and Human Recombinant UDP-Glucuronosyltransferases
Our understanding of human phase II metabolic pathways which facilitate detoxification and excretion of warfarin (Coumadin) is… 
2006
2006
The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose
AimsWarfarin is a frequently used anticoagulant drug with narrow therapeutic index and high interindividual variability in the… 
2005
2005
Kinetic study of cytochrome P450 3A4 activity on warfarin by capillary electrophoresis with fluorescence detection.
2001
2001
Quantitative liquid chromatography/mass spectrometry/mass spectrometry warfarin assay for in vitro cytochrome P450 studies.
A sensitive assay using high-performance liquid chromatography tandem mass spectrometry (MS/MS) has been established for the… 
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