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Furocoumarins

Known as: Furanocoumarin, Furocoumarins [Chemical/Ingredient], Furocoumarin 
A class of organic phytochemicals that consists of a furan ring fused with coumarin. Furanocoumarins are produced by plants as defensive toxins and… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (39)

1-thiopsoralen3-carbethoxyangelicin3-chloro-4-dimethylaminothioangelicin4',5'-dihydropsoralen
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Broader (4)

Dermatologic AgentsDyesPhotosensitizing AgentsPlant Extracts
FicusinIn BloodProcess of secretionagonists
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Distribution of C- and O-glycosyl flavonoids, (3-hydroxy-3-methylglutaryl)glycosyl flavanones and furocoumarins in Citrus aurantium L. juice
Abstract The qualitative and quantitative flavonoid and furocoumarin composition of crude sour orange (Citrus aurantium L.) juice… Expand
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Highly Cited
2008
Highly Cited
2008
Grapefruit juice and its furocoumarins inhibits autoinducer signaling and biofilm formation in bacteria.
Cell-to-cell communications in bacteria mediated by small diffusible molecules termed as autoinducers (AI) are known to influence… Expand
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Review
2004
Review
2004
Herbal bioactivation: The good, the bad and the ugly
Abstract It has been well established that the formation of reactive metabolites of drugs is associated with drug toxicity… Expand
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Highly Cited
2002
Highly Cited
2002
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
OBJECTIVES Our objective was to examine the effect of different fruits and their constituents on P-glycoprotein and organic anion… Expand
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Highly Cited
2002
Highly Cited
2002
Impact of folivory on photosynthesis is greater than the sum of its holes
The effects of herbivores on plant production and fitness may not relate directly to the quantity of biomass removed because… Expand
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Highly Cited
1999
Highly Cited
1999
Synthesis and antifungal activity of coumarins and angular furanocoumarins.
Angelicin, a naturally occurring furanocoumarin, that showed antifungal activity, was considered as a lead structure for a group… Expand
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Review
1998
Review
1998
Grapefruit juice-drug interactions.
The novel finding that grapefruit juice can markedly augment oral drug bioavailability was based on an unexpected observation… Expand
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Highly Cited
1997
Highly Cited
1997
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… Expand
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Highly Cited
1986
Highly Cited
1986
CONSTRAINTS ON CHEMICAL COEVOLUTION: WILD PARSNIPS AND THE PARSNIP WEBWORM.
The parsnip webworm (Depressaria pastinacella) and the wild parsnip (Pastinaca sativa) together represent a potentially… Expand
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Highly Cited
1984
Highly Cited
1984
Transcription of plant defence genes in response to UV light or fungal elicitor
The synthesis of secondary metabolites in response to stress conditions has been implicated as a major defence response of higher… Expand
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