FAQ

Furocoumarins

Known as: Furanocoumarin, Furocoumarins [Chemical/Ingredient], Furocoumarin 
A class of organic phytochemicals that consists of a furan ring fused with coumarin. Furanocoumarins are produced by plants as defensive toxins and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
05010019472017

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49 relations

Narrower (40)

1-thioangelicin1-thiopsoralen3-(alpha,alpha-dimethylallyl)psoralen4',5'-dihydropsoralen
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Broader (5)

Antifungal AgentsDermatologic AgentsDyesPlant Extracts
(More)
FicusinProcess of secretionantagonists & inhibitorschemical synthesis

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Furocoumarins
Antifungal Agents
Dyes
Plant Extracts
coumarin
chemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
OBJECTIVES Our objective was to examine the effect of different fruits and their constituents on P-glycoprotein and organic anion… (More)
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Highly Cited
2002
Highly Cited
2002
Impact of folivory on photosynthesis is greater than the sum of its holes.
The effects of herbivores on plant production and fitness may not relate directly to the quantity of biomass removed because… (More)
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Highly Cited
2000
Highly Cited
2000
Inhibition selectivity of grapefruit juice components on human cytochromes P450.
Five compounds including furanocoumarin monomers (bergamottin, 6', 7'-dihydroxybergamottin (DHB)), furanocoumarin dimers (4-¿¿6… (More)
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Highly Cited
2000
Highly Cited
2000
Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity.
With juices of grapefruit and related fruits, possible relationships between contents of six different furanocoumarins and… (More)
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Highly Cited
2000
Highly Cited
2000
Grapefruit-felodipine interaction: effect of unprocessed fruit and probable active ingredients.
OBJECTIVES To determine whether unprocessed grapefruit can cause a drug interaction, whether the active ingredients are naturally… (More)
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Highly Cited
1998
Highly Cited
1998
Chemical phenotype matching between a plant and its insect herbivore.
Two potential outcomes of a coevolutionary interaction are an escalating arms race and stable cycling. The general expectation… (More)
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Highly Cited
1998
Highly Cited
1998
Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.
Grapefruit juice has been found to significantly increase oral bioavailability of several drugs metabolized by cytochrome P450… (More)
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Highly Cited
1997
Highly Cited
1997
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… (More)
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Highly Cited
1986
Highly Cited
1986
Constraints on Chemical Coevolution: Wild Parsnips and the Parsnip Webworm.
The parsnip webworm (Depressaria pastinacella) and the wild parsnip (Pastinaca sativa) together represent a potentially… (More)
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Highly Cited
1984
Highly Cited
1984
Transcription of plant defence genes in response to UV light or fungal elicitor
The synthesis of secondary metabolites in response to stress conditions has been implicated as a major defence response of higher… (More)
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