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Furocoumarins

Known as: Furanocoumarin, Furocoumarins [Chemical/Ingredient], Furocoumarin 
A class of organic phytochemicals that consists of a furan ring fused with coumarin. Furanocoumarins are produced by plants as defensive toxins and… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (39)

1-thiopsoralen3-carbethoxyangelicin3-chloro-4-dimethylaminothioangelicin4',5'-dihydropsoralen

Broader (4)

Dermatologic AgentsDyesPhotosensitizing AgentsPlant Extracts
FicusinIn BloodProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Biofilms in the Food Industry: Health Aspects and Control Methods
Diverse microorganisms are able to grow on food matrixes and along food industry infrastructures. This growth may give rise to… 
Review
2008
Review
2008
A review of coumarin derivatives in pharmacotherapy of breast cancer.
The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in natural products (such as the anticoagulant warfarin… 
Review
2005
Review
2005
Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.
Coumarins, also known as benzopyrones, are present in remarkable amounts in plants, although their presence has also been… 
Review
2004
Review
2004
Clustered Pathway Genes in Aflatoxin Biosynthesis
Aflatoxins, a group of polyketide-derived furanocoumarins (Fig. [1][1]), are the most toxic and carcinogenic compounds among the… 
Highly Cited
2002
Highly Cited
2002
Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine
Our objective was to examine the effect of different fruits and their constituents on P‐glycoprotein and organic anion… 
Review
1998
Review
1998
Grapefruit juice-drug interactions.
The novel finding that grapefruit juice can markedly augment oral drug bioavailability was based on an unexpected observation… 
Highly Cited
1997
Highly Cited
1997
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… 
Review
1997
Review
1997
Drug Interactions with Grapefruit Juice
SummarySome drugs demonstrate a significantly greater (up to 3-fold) mean oral bioavailability on coadministration with… 
Highly Cited
1986
Highly Cited
1986
CONSTRAINTS ON CHEMICAL COEVOLUTION: WILD PARSNIPS AND THE PARSNIP WEBWORM
The parsnip webworm (Depressaria pastinacella) and the wild parsnip (Pastinaca sativa) together represent a potentially… 
Highly Cited
1984
Highly Cited
1984
Transcription of plant defence genes in response to UV light or fungal elicitor
The synthesis of secondary metabolites in response to stress conditions has been implicated as a major defence response of higher… 
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