• Publications
  • Influence
Reappraisal of the toxicology of ethylene glycol. II. Metabolism studies in laboratory animals.
Abstract The metabolism of ethylene glycol (EG) has been studied extensively in the albino rat and rhesus monkey ( Macaca mulatta ), and in a preliminary way in the chimpanzee, using both unlabelledExpand
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Carrageenan-induced squamous metaplasia of the rectal mucosa in the rat.
Degraded carrageenan, derived from Eucheuma spinosum, was administered to Sprague–Dawley rats as a solution in drinking water (5%; daily intake of carrageenan, 6 to 10 g per kg) or by stomach tubeExpand
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Implications for human health.
  • L. Golberg
  • Medicine
  • Environmental health perspectives
  • 1 October 1979
To analyze the implications for human health, the toxicologist requires four sets of data: the results of toxicity and other studies in animals; quantitative data on actual or potential humanExpand
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Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical study.
Non-invasive predictive assays which can confirm the presence or absence of hypoxic cells in human tumours show promise for understanding the natural history of tumour oxygenation, and improving theExpand
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Intestinal effects of carrageenans in the rhesus monkey (Macaca mulatta).
Abstract In a study in male and female rhesus monkeys ( Macaca mulatta ), the effects of a native form of carrageenan (HMR), derived from Chondrus crispus , have been compared with those of aExpand
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Hepatic Response to Lysosomal Effects of Hypoxia, Neutral Red and Chloroquine
THE histochemical detection of early changes in the characteristics, distribution and enzyme contents of lysosomes, as well as their cycles of appearance and disappearance, affords a sensitive indexExpand
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Uptake and storage of degraded carrageenan in lysosomes of reticuloendothelial cells of the rhesus monkey, Macaca mulatta.
Abstract Rhesus monkeys ( M. mulatta ) were given solutions of 1% HMR or of degraded carrageenan (2, 1, or 0.5% C16) as drinking water over a period of 7–11 weeks, followed by recovery for up to 24Expand
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A Clinical and Biochemical Study of Galactosaemia
The clinical syndrome of galactosaemia is now well known and more than 40 cases have been carefully described in the literature (Bell, Lindsay and Watson, 1950; Bray, Isaac and Watkins, -1952;Expand
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Imaging tumor hypoxia and tumor perfusion.
Tumor perfusion and oxygenation status have been suggested as factors which may influence treatment outcome in cancer patients. Nuclear medicine assays of tumor perfusionExpand
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Participation of lysosomes in early implantation in the rabbit.
Abstract Cytochemical and ultrastructural observations were made on the rabbit blastocyst, uterus (pregnant and nonpregnant), and implantation sites. In the blastocyst, acid phosphatase activity wasExpand
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