clinafloxacin

A series of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents were synthesized for the first… Expand

Type II topoisomerases alter DNA topology by forming a covalent DNA-cleavage complex that allows DNA transport through a double… Expand

Pseudomonas aeruginosa is one of the leading causes of nosocomial infections. Severe infections, such as pneumonia or bacteraemia… Expand

Toxicity tests were performed with seven fluoroquinolone antibiotics, ciprofloxacin, lomefloxacin, ofloxacin, levofloxacin… Expand

ObjectiveClinafloxacin is a novel quinolone with wide activity against the plethora of microorganisms encountered in… Expand

The history of the development of the quinolones is described from the first quinolone, nalidixic acid, via the first 6… Expand

ABSTRACT From 8,419 worldwide clinical isolates of Streptococcus pneumoniae obtained during 1997-1998, 69 isolates with reduced… Expand

ABSTRACT We examined the response of Streptococcus pneumoniae7785 to clinafloxacin, a novel C-8-substituted fluoroquinolone which… Expand

ABSTRACT On 10% oleic acid–albumin–dextrose–catalase-enriched 7H11 agar medium, the MIC at which 90% of the isolates are… Expand

The in-vitro activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and… Expand