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clinafloxacin

Known as: 3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Type II topoisomerases alter DNA topology by forming a covalent DNA-cleavage complex that allows DNA transport through a double… Expand
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Review
2005
Review
2005
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections. Severe infections, such as pneumonia or bacteraemia… Expand
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Highly Cited
2005
Highly Cited
2005
Toxicity tests were performed with seven fluoroquinolone antibiotics, ciprofloxacin, lomefloxacin, ofloxacin, levofloxacin… Expand
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2001
2001
OBJECTIVE Clinafloxacin is a novel quinolone with wide activity against the plethora of microorganisms encountered in… Expand
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Review
2000
Review
2000
The history of the development of the quinolones is described from the first quinolone, nalidixic acid, via the first 6… Expand
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Review
1999
Review
1999
Reactions of the gastrointestinal tract, the CNS and the skin are the most often observed adverse effects during therapy with… Expand
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Highly Cited
1998
Highly Cited
1998
We examined the response of Streptococcus pneumoniae 7785 to clinafloxacin, a novel C-8-substituted fluoroquinolone which is… Expand
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Highly Cited
1998
Highly Cited
1998
On 10% oleic acid-albumin-dextrose-catalase-enriched 7H11 agar medium, the MIC at which 90% of the isolates are inhibited for 20… Expand
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Highly Cited
1997
Highly Cited
1997
The in-vitro activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and… Expand
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Highly Cited
1997
Highly Cited
1997
Several Flavobacterium species, comprising a heterogeneous group of gram-negative bacilli that are capable of causing… Expand
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