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clinafloxacin

Known as: 3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
A series of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents were synthesized for the first… Expand
Highly Cited
2009
Highly Cited
2009
Type II topoisomerases alter DNA topology by forming a covalent DNA-cleavage complex that allows DNA transport through a double… Expand
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Review
2005
Review
2005
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections. Severe infections, such as pneumonia or bacteraemia… Expand
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Highly Cited
2005
Highly Cited
2005
Toxicity tests were performed with seven fluoroquinolone antibiotics, ciprofloxacin, lomefloxacin, ofloxacin, levofloxacin… Expand
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Highly Cited
2001
Highly Cited
2001
ObjectiveClinafloxacin is a novel quinolone with wide activity against the plethora of microorganisms encountered in… Expand
Review
2000
Review
2000
The history of the development of the quinolones is described from the first quinolone, nalidixic acid, via the first 6… Expand
Highly Cited
2000
Highly Cited
2000
ABSTRACT From 8,419 worldwide clinical isolates of Streptococcus pneumoniae obtained during 1997-1998, 69 isolates with reduced… Expand
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Highly Cited
1998
Highly Cited
1998
  • X. Pan, L. Fisher
  • Antimicrobial Agents and Chemotherapy
  • 1998
  • Corpus ID: 7960258
ABSTRACT We examined the response of Streptococcus pneumoniae7785 to clinafloxacin, a novel C-8-substituted fluoroquinolone which… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT On 10% oleic acid–albumin–dextrose–catalase-enriched 7H11 agar medium, the MIC at which 90% of the isolates are… Expand
Highly Cited
1997
Highly Cited
1997
  • A. Bauernfeind
  • The Journal of antimicrobial chemotherapy
  • 1997
  • Corpus ID: 32293846
The in-vitro activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and… Expand