Fluoroquinolones

Known as: Fluoroquinolone, Fluoroquinolone Antibiotic, Fluoroquinolones [Chemical/Ingredient] 
Any quinolone antibiotic with a fluorine (F) atom attached to the quinolone structure, with broad-spectrum antibacterial activity. Fluoroquinolones… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Antimicrobial-modifying resistance enzymes have traditionally been class specific, having coevolved with the antibiotics they… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Since 2002, an epidemic of Clostridium difficile-associated-diarrhea (CDAD) associated with a high case-fatality rate… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AND OBJECTIVE Fluoroquinolones have not been frequently implicated as a cause of Clostridium difficile outbreaks… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND In March 2003, several hospitals in Quebec, Canada, noted a marked increase in the incidence of Clostridium difficile… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT Previous surveillance studies have documented increasing rates of antimicrobial resistance in US intensive care units… (More)
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Review
2003
Review
2003
Although the fluoroquinolones are presently used to treat tuberculosis primarily in cases involving resistance or intolerance to… (More)
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Review
2003
Review
2003
Fluoroquinolones trap gyrase and topoisomerase IV on DNA as ternary complexes that block the movement of replication forks and… (More)
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Review
2001
Review
2001
Broad use of fluoroquinolones has been followed by emergence of resistance, which has been due mainly to chromosomal mutations in… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Fluoroquinolones are now recommended for the treatment of respiratory tract infections due to Streptococcus pneumoniae… (More)
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Review
1996
Review
1996
The fluoroquinolones are a series of synthetic antibacterial agents that are undergoing extensive investigation for both human… (More)
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