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The Crisis in Antibiotic Resistance
- H. Neu
- Medicine, BiologyScience
- 21 August 1992
Mechanisms such as antibiotic control programs, better hygiene, and synthesis of agents with improved antimicrobial activity need to be adopted in order to limit bacterial resistance.
The release of enzymes from Escherichia coli by osmotic shock and during the formation of spheroplasts.
Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria
Ciprofloxacin was 4- to 32-fold more active than norfloxACin and inhibited gentamicin-, ameikacin-, cefotaxime-, and moxalactam-resistant members of the family Enterobacteriaceae and P. aeruginosa and methicillin-resistant Staphylococcus aureus.
Quinolone antimicrobial agents.
- H. Neu
- Biology, MedicineAnnual review of medicine
The molecular and clinical problems of bacterial resistance are reviewed and the clinical areas in which fluoroquinolones have been investigated are detailed, with particular attention to areas of appropriate and inappropriate use.
Cefamandole, a Cephalosporin Antibiotic with an Unusually Wide Spectrum of Activity
- H. Neu
- Biology, MedicineAntimicrobial Agents and Chemotherapy
- 1 August 1974
Inoculum size and type of medium had variable effects on the minimal inhibitory concentration, depending upon the particular strain tested, and strains of Enterobacter, Serratia, indole-positive Proteus species showed the greatest inoculum effect.
National epidemiology of mycoses survey: a multicenter study of strain variation and antifungal susceptibility among isolates of Candida species.
In the immunosuppressed, gastrointestinal histoplasmosis must be considered, even in a patient from a nonendemic area, who presents with lesions appearing like carcinoma or inflammatory bowel disease, which often mimicinflammatory bowel disease or carcinoma.
The new beta-lactamase-stable cephalosporins.
- H. Neu
- BiologyAnnals of internal medicine
- 1 September 1982
The proliferation of new beta-lactam compounds is due to the increased resistance of gram-negative bacteria to existing compounds, an increased awareness of the toxic potential of other compounds, and an increased attention to the role of non-volatile materials in food spoilage.
ORAL CIPROFLOXACIN THERAPY OF INFECTIONS DUE TO PSEUDOMONAS AERUGINOSA