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The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals.
BACKGROUND It has been suggested that a low dietary intake of antioxidant vitamins and minerals increases the incidence rate of cardiovascular disease and cancer. To date, however, the published… Expand
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
- S. Mouret, C. Baudouin, M. Charvéron, A. Favier, J. Cadet, T. Douki
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 12 September 2006
Solar UV radiation is the most important environmental factor involved in the pathogenesis of skin cancers. The well known genotoxic properties of UVB radiation (290–320 nm) mostly involve… Expand
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules.
SLC30A8, a novel member of the zinc transporter (ZnT) family, was identified by searching the human genomic and expressed sequence tag (EST) databases with the amino acid sequence of all known human… Expand
Serum concentrations of β-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population
- P. Galán, F. Viteri, +9 authors S. Hercberg
- European Journal of Clinical Nutrition
- 1 October 2005
Objective:To assess relationships between energy, nutrient and food intakes, alcohol consumption, smoking status and body mass index (BMI), and serum concentrations of β-carotene, α-tocopherol,… Expand
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
- F. Chimienti, S. Devergnas, +8 authors M. Seve
- Biology, Medicine
- Journal of Cell Science
- 15 October 2006
Insulin-secreting pancreatic beta cells are exceptionally rich in zinc. In these cells, zinc is required for zinc-insulin crystallization within secretory vesicles. Secreted zinc has also been… Expand
Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults.
- S. Czernichow, A. Vergnaud, +6 authors N. Ahluwalia
- The American journal of clinical nutrition
- 1 August 2009
BACKGROUND Limited observational evidence suggests lower antioxidant concentrations in individuals with the metabolic syndrome (MetS); few randomized controlled trials have addressed the effect of… Expand
Le stress oxydant : Intérêt conceptuel et expérimental dans la compréhension des mécanismes des maladies et potentiel thérapeutique
- A. Favier
The oxidative stress: concept and experimental interest to understand diseases mechanisms and therapeutic approaches Free radicals and their precursors are members of a reactive chemical family named… Expand
Determining factors in the iron status of adult women in the SU.VI.MAX study
The iron status of a national sample of adults living in France and participating in the SU.VI.MAX cohort, was assessed using serum ferritin and hemoglobin concentrations. Complete data were obtained… Expand
Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis.
- S. Amara, H. Abdelmelek, +6 authors K. Ben Rhouma
- Medicine, Biology
- The Journal of reproduction and development
- 1 April 2008
The aim of this study was to investigate the antioxidant role of zinc (Zn) in the Cd-exposed testes of Wistar rats. Subchronic exposure to Cd (CdCl(2), 40 mg/l, per os) for 30 days resulted in a… Expand
Prion infection impairs the cellular response to oxidative stress.
- O. Milhavet, H. Mcmahon, +8 authors S. Lehmann
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 5 December 2000
The molecular mechanism of neurodegeneration in transmissible spongiform encephalopathies remains uncertain. In this study, it was demonstrated that prion-infected hypothalamic neuronal GT1 cells… Expand