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The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals.
BACKGROUND It has been suggested that a low dietary intake of antioxidant vitamins and minerals increases the incidence rate of cardiovascular disease and cancer. To date, however, the publishedExpand
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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
Solar UV radiation is the most important environmental factor involved in the pathogenesis of skin cancers. The well known genotoxic properties of UVB radiation (290–320 nm) mostly involveExpand
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Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules.
SLC30A8, a novel member of the zinc transporter (ZnT) family, was identified by searching the human genomic and expressed sequence tag (EST) databases with the amino acid sequence of all known humanExpand
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Serum concentrations of β-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population
Objective:To assess relationships between energy, nutrient and food intakes, alcohol consumption, smoking status and body mass index (BMI), and serum concentrations of β-carotene, α-tocopherol,Expand
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In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
Insulin-secreting pancreatic beta cells are exceptionally rich in zinc. In these cells, zinc is required for zinc-insulin crystallization within secretory vesicles. Secreted zinc has also beenExpand
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Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults.
BACKGROUND Limited observational evidence suggests lower antioxidant concentrations in individuals with the metabolic syndrome (MetS); few randomized controlled trials have addressed the effect ofExpand
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Le stress oxydant : Intérêt conceptuel et expérimental dans la compréhension des mécanismes des maladies et potentiel thérapeutique
The oxidative stress: concept and experimental interest to understand diseases mechanisms and therapeutic approaches Free radicals and their precursors are members of a reactive chemical family namedExpand
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Determining factors in the iron status of adult women in the SU.VI.MAX study
The iron status of a national sample of adults living in France and participating in the SU.VI.MAX cohort, was assessed using serum ferritin and hemoglobin concentrations. Complete data were obtainedExpand
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Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis.
The aim of this study was to investigate the antioxidant role of zinc (Zn) in the Cd-exposed testes of Wistar rats. Subchronic exposure to Cd (CdCl(2), 40 mg/l, per os) for 30 days resulted in aExpand
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Prion infection impairs the cellular response to oxidative stress.
The molecular mechanism of neurodegeneration in transmissible spongiform encephalopathies remains uncertain. In this study, it was demonstrated that prion-infected hypothalamic neuronal GT1 cellsExpand
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