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Rapid Identification and Typing of Listeria Species by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
ABSTRACT Listeria monocytogenes is a food-borne pathogen that is the causative agent of human listeriosis, an opportunistic infection that primarily infects pregnant women and immunologicallyExpand
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A Novel Approach of Direct Ex Vivo Epitope Mapping Identifies Dominant and Subdominant CD4 and CD8 T Cell Epitopes from Listeria monocytogenes1
We used a novel approach for the direct ex vivo identification and characterization of T cell epitopes based on the screening of peptide spot libraries with freshly isolated splenocytes in aExpand
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Management of listeriosis.
Determination of the MIC in vitro is often used as the basis for predicting the clinical efficacy of antibiotics. Listeriae are uniformly susceptible in vitro to most common antibiotics exceptExpand
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Current Diagnosis and Treatment of Spondylodiscitis
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Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low‐dose mouse infection model
Gliotoxin is a secondary metabolite produced by several fungi including the opportunistic human pathogen Aspergillus fumigatus. As gliotoxin exerts immunosuppressive effects in vitro and in vivo, aExpand
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Diagnosis of invasive fungal infections in hematology and oncology--guidelines from the Infectious Diseases Working Party in Haematology and Oncology of the German Society for Haematology and
Invasive fungal infections (IFIs) are a primary cause of morbidity and mortality in patients with hematological malignancies. Establishing a definite diagnosis of IFI in immunocompromised patients isExpand
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History and epidemiology of listeriosis.
  • H. Hof
  • Biology, Medicine
  • FEMS immunology and medical microbiology
  • 1 April 2003
Listeriae are used as a tool by different specialities in biomedical research. There are now at least four major fields of interest in Listeria: (1). the role in medical microbiology: ListeriaExpand
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An update on the medical management of listeriosis
  • H. Hof
  • Medicine
  • Expert opinion on pharmacotherapy
  • 1 August 2004
It is still not quite well understood why there is no optimal or even a satisfactory antibiotic therapy for listeriosis. Although almost all Listeria strains that induce sepsis, meningitis andExpand
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Critical Annotations to the Use of Azole Antifungals for Plant Protection
  • H. Hof
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • 1 November 2001
Fungal infections of plants cause a considerable loss of crop yields worldwide. In addition some fungi, such as Fusarium spp., while growing on plants are able to produce mycotoxins which canExpand
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  • PDF
A new, broad‐spectrum azole antifungal: posaconazole – mechanisms of action and resistance, spectrum of activity
  • H. Hof
  • Chemistry, Medicine
  • Mycoses
  • 6 September 2006
Posaconazole, a new triazole antifungal, exerts principally the same mechanism of action as the other azole derivatives, i.e. it inhibits the ergosterol production by binding and inhibiting theExpand
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