aclacinomycins

Known as: Aclacinomycin Antitumor Antibiotic 
An oligosaccharide anthracycline antibiotic isolated from strains of the bacterium Streptomyces galilaeus with potential antineoplastic activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2005
012319752005

Papers overview

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2005
2005
During biosynthesis of the anthracycline antitumor agents daunomycin, adriamycin, and aclacinomycin, the polyketide-derived… (More)
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2002
2002
We have cloned and sequenced polyketide synthase (PKS) genes from the aclacinomycin producer Streptomyces galilaeus ATCC 31,615… (More)
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2002
2002
In this study a set of Streptomyces galilaeus ATCC 31615 mutants was characterized, which are incapable of synthesizing some or… (More)
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2000
2000
The genes rdmB and rdmC of Streptomyces purpurascens encoding aclacinomycin modifying enzymes RdmB and RdmC were expressed in… (More)
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1994
1994
Twelve mutants of Streptomyces galilaeus (ATCC 31615) blocked in the production of aclacinomycin A, an anthracycline antibiotic… (More)
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1994
1994
Aclacinomycins A and B are anthracycline antibiotics with potent antitumor activity. Each consists of an alkavinone aglycon… (More)
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1981
1981
Anthracycline antibiotics aclacinomycins (ACMs) are aklavinone glycosides with variation in the trisaccharide moiety and were… (More)
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1980
1980
An aclacinomycin-negative mutant strain KE303 which required aklavinone aglycone for the production of anthracycline antibiotics… (More)
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1979
1979
In the preceding papers1~4) we have reported Streptomyces galilaeus MA144-M1to produce new antitumor anthracycline antibiotics… (More)
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