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Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917. Production, isolation, structure elucidation, and biological activity.
Aurantimycins were isolated from the mycelium of Streptomyces aurantiacus JA 4570 as new representatives of the azinothricin group of hexadepsipeptide antibiotics and display strong activity against Gram-positive bacteria and cytotoxic effects against L-929 mouse fibroblast cells. Expand
Epicorazine C, an antimicrobial metabolite from Stereum hirsutum HKI 0195.
In the course of screening for new antibiotics active against methicillin-resistant Staphylococcus aureus, we isolated an antibacterial metabolite from the culture broth of a basidiomycete, which wasExpand
Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101.
Four new members of peptaibol antibiotics were isolated from the mycelium of Apiocrea chrysosperma Ap101 by solvent extraction, silica gel chromatography and preparative recycling HPLC, showing antibacterial and antifungal activity and induce pigment formation by the fungus Phoma destructiva. Expand
Roseoferin, a new aminolipopeptide antibiotic complex from Mycogone rosea DSM 12973, structures and biological activities.
The complex of at least 16 closely related aminolipopeptide antibiotics named roseoferin was chromatographically inseparable but structural assignment of every of these components was possible on the basis of tandem mass spectrometry. Expand
Tetramycin B, a new polyene macrolide antibiotic: The structure of tetramycins A and B as studied by high-field NMR spectroscopy
Abstract The complete assignment of 13 C and 400 MHz proton NMR spectra provides corroboration for earlier structural proposals for tetramycin (tetramycin A), a tetraene macrolide antibiotic, andExpand
Formation of membrane pores by aurantimycins A and B, new lipopeptide antibiotics from Streptomyces aurantiacus
Abstract Aurantimycins A and B are novel lipopeptide-type antibiotics forming channels through an artificial membrane in above 0.1 μM concentration. Electric conductivity of the bilayer increasedExpand
Tetramycin, a new polyene antibiotic.
A new polyene antibiotic was isolated from the culture broth of a new Streptomyces and named tetramycin, and the isolation, purification, physiochemical, and biological properties of the antibiotic are described. Expand
Isolation and structures of nitrogen-free platenolide glycosides. I. The 5-O-(deoxy-3'-C-acetyl-beta-D-hexopyranosyl)-platenolides I and II.
Four novel nitrogen-free glycosides of platenolides I and II were isolated as secondary shunt metabolites of the turimycin biosynthesis from the culture broth of an industrial strain of StreptomycesExpand