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High production of prodigiosin by Serratia marcescens grown on ethanol
Serratia marcescens S389, isolated as an ethanol-utilizing bacterium, produced prodigiosin at up to 3 mg ml−1 when grown on ethanol and with the omission of inorganic phosphate and NaCl from the…
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Insight into functional diversity of cytochrome P450 in the white-rot basidiomycete Phanerochaete chrysosporium: involvement of versatile monooxygenase.
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Anthracycline metabolites from Streptomyces violaceus A262. I. Isolation of antibiotic-blocked mutants from Streptomyces violaceus A262.
TLDR
Five mutant (or variant) strains producing new anthracycline antibiotics were derived from Streptomyces violaceus A262 by mutagenesis treatment and preliminary identification of their anthrACYcline products are described.
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Cloning and characterization of a glycosyltransferase gene involved in the biosynthesis of anthracycline antibiotic beta-rhodomycin from Streptomyces violaceus.
TLDR
Results indicated that rhoG is the Glycosyltransferase gene responsible for the glycosylation of epsilon-rhodomycinone in beta-r Rhodomycin biosynthesis.
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The Fibrinolytic Activity of a Novel Protease Derived from a Tempeh Producing Fungus, Fusarium sp. BLB
TLDR
Results suggest that FP is superior to Nattokinases in dissolving fibrin when absorbed into the blood, and the predicted amino acid sequence of FP showed highest homology, with that of trypsin from Fusarium oxysporum.
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Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor.
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New anthracycline antibiotics obtained by microbial glycosidation of beta-isorhodomycinone and alpha 2-rhodomycinone.
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Anthracycline metabolites from Streptomyces violaceus A262. III. New anthracycline obelmycins produced by a variant strain SE2-2385.
TLDR
New anthracycline antibiotics, designated as obelmycins A, D, E, F and G, were isolated from the culture broth of a variant strain of beta-rhodomycin-producing Streptomyces violaceus A262 and assayed for their in vitro cytotoxicities against murine leukemic L1210 cell culture and the antimicrobial activities in comparison with some known anthRacyclines.
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Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunorubicin-producing microorganism.
A new potent anthracycline antibiotic oxaunomycin was isolated from the culture broth of a blocked mutant derived from a baumycin producer and was identified as…
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The Antitumor Drug Aclacinomycin A, Which Inhibits the Degradation of Ubiquitinated Proteins, Shows Selectivity for the Chymotrypsin-like Activity of the Bovine Pituitary 20 S Proteasome*
TLDR
Aclacinomycin A is the first described non-peptidic inhibitor showing discrete selectivity for the chymotrypsin-like activity of the 20 S proteasome.
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