Improvement of kasugamycin-producing strain by the agar piece method and the prototroph method
named kasugamine and a side-chain containing carboxyl and amino groups shows a preventive effect against rice blast in the field and has no toxicity for humans, other mammals and fish.
Proline hydroxylation by cell free extract of a streptomycete.
Holomycin and N-propionylholothin, antibiotics produced by a cephamycin C producer.
- K. Okamura, K. Soga, Y. Shimauchi, T. Ishikura, J. Lein
- Medicine, BiologyJournal of antibiotics (Tokyo. )
- 1 April 1977
It was previously found that Streptomyces sp. P6621 which was isolated by us from soil produces cephamycin C.1) A nitrosoguanidine mutant of this culture designated P6621-7N49 was found to produce…
Anthracycline metabolites from Streptomyces violaceus A262. I. Isolation of antibiotic-blocked mutants from Streptomyces violaceus A262.
- O. Johdo, T. Ishikura, A. Yoshimoto, T. Takeuchi
- Chemistry, BiologyThe Journal of antibiotics
- 25 October 1991
Five mutant (or variant) strains producing new anthracycline antibiotics were derived from Streptomyces violaceus A262 by mutagenesis treatment and preliminary identification of their anthrACYcline products are described.
Incorporation of Molecular Oxygen during Microbial Utilization of Olefins
THE utilization of various alkanes by certain bacteria involves the incorporation of molecular oxygen into the conversion products1 and into the bacterial cells2. The attack of the olefin…
Deacetylation of PS-5, a new beta-lactam compound. III. Enzymological characterization of L-amino acid acylase and D-amino acid acylase from Pseudomonas sp. 1158.
P-Chloromercuribenzoate inhibited both enzymes, whereas ethylenediamine tetraacetate was very inhibitory on L-amino acid acylase only, and with N-acetyl- and N-chloroacetyl -amino acids as substrates, they were relatively stereo-specific.
PS-5 inhibition of a beta-lactamase from Proteus vulgaris.
PS-5 was very slowly hydrolyzed by the enzyme, showing a triphasic pattern in its reaction curve, and inhibited the beta-lactamase by formation of a Michaelis-complex.
Determination of CGTase from Bacillus ohbensis and Its Optimum pH Using HPLC
The a-cyclo-dextrm formation after a complex of oc-cyclodextrm and iodine forms, this method cannot be used for CGTase that gives /?-cyclodextrm as the main product The glucoamylase method is an…
Comparative Studies of CGTases from Bacillus ohbensis, Bacillus macerans and Bacillus circulans and Production of Cyclodextrins Using Those CGTases
Comparative studies of three CGTases revealed that the CGTase from B. ohbensis had the smallest molecular weight and low affinity on starch adsorption while in other properties, i.e., optimum pH, pH stability, optimum temperature and etc., the three enzymes showed similar properties.