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Improvement of kasugamycin-producing strain by the agar piece method and the prototroph method
named kasugamine and a side-chain containing carboxyl and amino groups shows a preventive effect against rice blast in the field and has no toxicity for humans, other mammals and fish. Expand
Proline hydroxylation by cell free extract of a streptomycete.
Free L-proline was hydroxylated to free L-hydroxyproline by cell free extract of Streptomyces griseoviridus P8648 and zinc ion, ethylenediaminetetraacetic acid and alpha,alpha'-dipyridyl inhibited the reaction. Expand
Anthracycline metabolites from Streptomyces violaceus A262. I. Isolation of antibiotic-blocked mutants from Streptomyces violaceus A262.
Five mutant (or variant) strains producing new anthracycline antibiotics were derived from Streptomyces violaceus A262 by mutagenesis treatment and preliminary identification of their anthrACYcline products are described. Expand
Incorporation of Molecular Oxygen during Microbial Utilization of Olefins
THE utilization of various alkanes by certain bacteria involves the incorporation of molecular oxygen into the conversion products1 and into the bacterial cells2. The attack of the olefinExpand
Deacetylation of PS-5, a new beta-lactam compound. III. Enzymological characterization of L-amino acid acylase and D-amino acid acylase from Pseudomonas sp. 1158.
P-Chloromercuribenzoate inhibited both enzymes, whereas ethylenediamine tetraacetate was very inhibitory on L-amino acid acylase only, and with N-acetyl- and N-chloroacetyl -amino acids as substrates, they were relatively stereo-specific. Expand
Comparative Studies of CGTases from Bacillus ohbensis, Bacillus macerans and Bacillus circulans and Production of Cyclodextrins Using Those CGTases
Three kinds of cyclomaltodextrin glucanotransferases (CGTases) produced by Bacillus ohbensis, Bacillus macerans and Bacillus circulans were respectively purified to a single protein and the CGTaseExpand
Anthracycline metabolites from Streptomyces violaceus A262. III. New anthracycline obelmycins produced by a variant strain SE2-2385.
New anthracycline antibiotics, designated as obelmycins A, D, E, F and G, were isolated from the culture broth of a variant strain of beta-rhodomycin-producing Streptomyces violaceus A262 and assayed for their in vitro cytotoxicities against murine leukemic L1210 cell culture and the antimicrobial activities in comparison with some known anthRacyclines. Expand