FAQ

aclacinomycin B

Known as: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester,(1R-(1-alpha,2-beta,4-beta))-, Aclarubicin B 
An antineoplastic oligosaccharide anthracycline antibiotic isolated from the bacterium Streptomyces galilaeus. Aclacinomycin B intercalates into DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2005
02419772005

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1 relation

Broader (1)

aclacinomycins

Related mentions per year

Related mentions per year

1975-2006
19701980199020002010
aclacinomycin B
aclacinomycins

Papers overview

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2005
2005
In vivo antitumor efficacy and cardiotoxicity of novel anthracycline ID6105 (11-hydroxy-aclacinomycin X, Hyrubicin)
Hybrid biosynthetic approach produced a new anthracycline ID6105 (11-hydroxyaclacinomycin X, Hyrubicin), which has potent… (More)
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1996
1996
Aclacinomycin X, a novel anthracycline antibiotic produced by Streptomyces galilaeus ATCC 31133.
A new anthracycline antibiotic, designated as aclacinomycin X, was isolated from the culture broth of Streptomyces galilaeus ATCC… (More)
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1991
1991
Determination of DNA topoisomerase II activity from L1210 cells--a target for screening antitumor agents.
DNA topoisomerase II was isolated from mouse leukemia L1210 cells and the activity was determined by using P4 phage knotted DNA… (More)
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1985
1985
Phase II evaluation of aclacinomycin-A in patients with adenocarcinoma and large cell carcinoma of the lung.
Aclacinomycin-A (ACLA-A), the new anthracycline antibiotic that produces substantially less cardiotoxicity relative to… (More)
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1984
1984
Phase II evaluation of aclacinomycin-A (NSC-208734) in adenocarcinoma of the kidney.
 
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1983
1983
Delivery of aclacinomycin A to human glioma cells in vitro by the low-density lipoprotein pathway.
The present study shows that a human malignant glioma cell line (U-251 MG) accumulates and degrades low-density lipoprotein (LDL… (More)
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1983
1983
Possible differentiation of human acute myeloblastic leukemia cells by daily and intermittent administration of aclacinomycin-A.
A rapid decrease of myeloblasts and a remarkable increase of mature neutrophils, mostly with Pelger anomaly, were observed in the… (More)
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1980
1980
[Studies on the absorption, excretion and distribution of aclacinomycin A: absorption, excretion and distribution of 14C- or 3H-aclacinomycin A in mice, rats and rabbits (author's transl)].
A new anthracycline antitumor antibiotic, aclacinomycin A, was labeled with 3H uniformly or with 14C simultaneously at the… (More)
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1979
1979
Combination chemotherapy with a new anthracycline glycoside, aclacinomycin-A, and active drugs for malignant lymphomas in P388 mouse leukemia system.
Aclacinomycin-A is a new anthracycline glycoside and has less cardiotoxicity than adriamycin. In an attempt to provide an… (More)
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1977
1977
Antitumor activity of new anthracycline antibiotics, aclacinomycin-A and its analogs, and their toxicity.
New anthracycline antibiotics have been isolated from the culture of Streptomyces galilaeus MA144-M1. Among 14 anthracycline… (More)
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