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VCL gene

Known as: Vinculin Gene, VCL, VINCULIN 
This gene plays a role in cytoskeletal regulation and cellular adhesion.
National Institutes of Health

Related topics

Related topics

6 relations
Cell AdhesionLigand BindingTumor SuppressionVCL protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Force transduction by Triton cytoskeletons
Force-initiated signal transduction can occur either via membrane-based ionic mechanisms or through changes in cytoskeletal… 
Highly Cited
1999
Highly Cited
1999
The LIM-Only Protein PINCH Directly Interacts with Integrin-Linked Kinase and Is Recruited to Integrin-Rich Sites in Spreading Cells
ABSTRACT PINCH is a widely expressed and evolutionarily conserved protein comprising primarily five LIM domains, which are… 
Highly Cited
1998
Highly Cited
1998
α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells
αE-catenin, a cadherin-associated protein, is required for tight junction (TJ) organization, but its role is poorly understood… 
Highly Cited
1992
Highly Cited
1992
Protein kinase C involvement in focal adhesion formation.
Matrix molecules such as fibronectin can promote cell attachment, spreading and focal adhesion formation. Although some… 
Highly Cited
1991
Highly Cited
1991
The uvomorulin-anchorage protein alpha catenin is a vinculin homologue.
The cytoplasmic region of the Ca(2+)-dependent cell-adhesion molecule (CAM) uvomorulin associates with distinct cytoplasmic… 
Highly Cited
1991
Highly Cited
1991
Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
We investigated the role of the integrins alpha v beta 3 and alpha v beta 5 in mediating vitronectin adhesion of three… 
Highly Cited
1990
Highly Cited
1990
Paxillin: a new vinculin-binding protein present in focal adhesions
The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers… 
Highly Cited
1985
Highly Cited
1985
Development of cell surface linkage complexes in cultured fibroblasts
The possible role of a 140K membrane-associated protein complex (140K) in fibronectin-cytoskeleton associations has been examined… 
Highly Cited
1984
Highly Cited
1984
A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells
Treatment of epithelial African green monkey kidney (BSC-1) cells with the potent tumor promoter 12-O-tetradecanoylphorbol-13… 
Highly Cited
1981
Highly Cited
1981
Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth…
The ultrastructural localization of three cytoskeletal proteins, alpha- actinin, tropomyosin, and vinculin, in the brush border… 
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