Skip to search formSkip to main contentSkip to account menu

Tumor Promoters

Known as: Promoters, Tumor, Tumor Promoter 
An agent that acts at stage 2 of carcinogenesis, following the initiation of increased cell proliferation. It is a necessary step in overt tumor… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Carcinogens
Neoplastic ProcessesTumor Progression

Narrower (3)

Okadaic AcidPhorbolsThapsigargin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation.
An mRNA differential display comparison of mouse JB6 promotion-sensitive (P+) and -resistant (P-) cells identified a novel gene… 
Highly Cited
1997
Highly Cited
1997
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
(-)-Epigallocatechin gallate (EGCG) and theaflavins are believed to be key active components in tea for the chemoprevention… 
Highly Cited
1996
Highly Cited
1996
Frequent clones of p53-mutated keratinocytes in normal human skin.
The multiple genetic hit model of cancer predicts that normal individuals should have stable populations of cancer-prone, but… 
Highly Cited
1995
Highly Cited
1995
c-fos is required for malignant progression of skin tumors
Highly Cited
1994
Highly Cited
1994
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
AP-1 transcriptional activity is stimulated by the transformation promoters phorbol 12-myristate 13-acetate ("12-O… 
Highly Cited
1988
Highly Cited
1988
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
Okadaic acid is a polyether compound of a C38 fatty acid, isolated from a black sponge, Halichondria okadai. Previous studies… 
Highly Cited
1987
Highly Cited
1987
12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region
Genomic clones coding for human fibroblast collagenase were isolated. By constructing and transfecting mutants with 5' and 3… 
Highly Cited
1984
Highly Cited
1984
A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells
Treatment of epithelial African green monkey kidney (BSC-1) cells with the potent tumor promoter 12-O-tetradecanoylphorbol-13… 
Highly Cited
1983
Highly Cited
1983
Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.
Highly Cited
1979
Highly Cited
1979
Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter.
Wild-type Chinese hamster V79 cells (6-thioguanine-sensitive) reduce the recovery of 6-thioguanine-resistant cells when they are… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)