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Okadaic Acid

Known as: Acid, Ocadaic, Acid, Okadaic, OKA 
A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 &amp… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (4)

7-deoxyokadaic acidbelizeanic acidcorozalic acidokadaic acid diol ester

Broader (9)

CarcinogensEnzyme InhibitorsEthersEthers, Cyclic
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
First evidence of spirolides in Spanish shellfish.
Highly Cited
2000
Highly Cited
2000
Assay for redox-sensitive transcription factor.
Highly Cited
1998
Highly Cited
1998
A Novel Protein Phosphatase That Dephosphorylates and Regulates Ca2+/Calmodulin-dependent Protein Kinase II*
A synthetic peptide corresponding to the autophosphorylation site of Ca2+/calmodulin-dependent protein kinase II (CaMKII… 
Highly Cited
1997
Highly Cited
1997
Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A
Highly Cited
1994
Highly Cited
1994
A role for protein kinases and phosphatases in the Ca2+-induced enhancement of hippocampal AMPA receptor-mediated synaptic responses
Highly Cited
1992
Highly Cited
1992
Localized Ca2+ entry preferentially effects protein dephosphorylation, phosphorylation, and glutamate release.
Highly Cited
1991
Highly Cited
1991
Tyrosine phosphorylation of p34cdc2 and p42 during meiotic maturation of Xenopus oocyte. Antagonistic action of okadaic acid and 6-DMAP.
The tyrosine phosphorylation/dephosphorylation of p34cdc2 was estimated by immunoblotting with antiphosphotyrosine antibody… 
Highly Cited
1990
Highly Cited
1990
Sucrose‐phosphate synthase is dephosphorylated by protein phosphatase 2A in spinach leaves
Highly Cited
1989
Highly Cited
1989
An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues
Highly Cited
1975
Highly Cited
1975
Development of a live attenuated varicella vaccine.
The Oka strain of varicella virus, isolated in our labolatory, was serially cultivated in guinea-pig embryo cultures (GPEC), and… 
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