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Tumor Progression

Known as: cancer progression, neoplasm progression, neoplastic progression 
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Cancers develop in complex tissue environments, which they depend on for sustained growth, invasion and metastasis. Unlike tumor… Expand
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Review
2007
Review
2007
Aberrant gene function and altered patterns of gene expression are key features of cancer. Growing evidence shows that acquired… Expand
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Review
2005
Review
2005
Epithelial-mesenchymal transitions (EMTs) occur as key steps during embryonic morphogenesis, and are now implicated in the… Expand
Highly Cited
2004
Highly Cited
2004
The RAS/RAF signaling pathway is an important mediator of tumor cell proliferation and angiogenesis. The novel bi-aryl urea BAY… Expand
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Highly Cited
2001
Highly Cited
2001
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin and the stages of progression of this… Expand
Highly Cited
2001
Highly Cited
2001
Epithelial and hematopoietic cells have a high turnover and their progenitor cells divide continuously, making them prime targets… Expand
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Review
2000
Review
2000
  • P. Polakis
  • Genes & development
  • 2000
  • Corpus ID: 14960846
The regulation of cell growth and survival can be subverted by a variety of genetic defects that alter transcriptional programs… Expand
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Review
1996
Review
1996
The authors are grateful to the members of their laboratories for their contributions to the reviewed studies and for their… Expand
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Highly Cited
1988
Highly Cited
1988
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… Expand
Highly Cited
1976
Highly Cited
1976
It is proposed that most neoplasms arise from a single cell of origin, and tumor progression results from acquired genetic… Expand