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Tumor Progression

Known as: cancer progression, neoplasm progression, neoplastic progression 
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Cancers develop in complex tissue environments, which they depend on for sustained growth, invasion and metastasis. Unlike tumor… 
Review
2007
Review
2007
Highly Cited
2004
Highly Cited
2004
The RAS/RAF signaling pathway is an important mediator of tumor cell proliferation and angiogenesis. The novel bi-aryl urea BAY… 
Highly Cited
2004
Highly Cited
2004
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell… 
Highly Cited
2001
Highly Cited
2001
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin and the stages of progression of this… 
Highly Cited
2001
Highly Cited
2001
In human breast carcinomas, overexpression of the macrophage colony–stimulating factor (CSF-1) and its receptor (CSF-1R… 
Highly Cited
2001
Highly Cited
2001
Epithelial and hematopoietic cells have a high turnover and their progenitor cells divide continuously, making them prime targets… 
Review
1996
Highly Cited
1988
Highly Cited
1988
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… 
Highly Cited
1976
Highly Cited
1976
It is proposed that most neoplasms arise from a single cell of origin, and tumor progression results from acquired genetic…