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Neoplastic Cell Transformation

Known as: neoplastic transformation, Cell Transformation, Neoplastic, Cell Neoplastic Transformation 
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities… Expand
National Institutes of Health

Related topics

Related topics

50 relations
AML1/TEL FUSION GENEANP32C protein, humanANP32C wt AlleleARHGEF5 gene
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Broader (1)

metaplastic cell transformation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Involvement of the long noncoding RNA NEAT1 in carcinogenesis
Altered expression levels of the long noncoding RNA (lncRNA) nuclear‐enriched abundant transcript 1 (NEAT1) have been reported in… Expand
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Review
2019
Review
2019
WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis
The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of… Expand
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Review
2019
Review
2019
Diverging inflammasome signals in tumorigenesis and potential targeting
Inflammasomes are molecular platforms that assemble upon sensing various intracellular stimuli. Inflammasome assembly leads to… Expand
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Review
2018
Review
2018
Hijacking of the AP-1 Signaling Pathway during Development of ATL
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy known as adult T-cell leukemia (ATL… Expand
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Review
2018
Review
2018
The Anti-Inflammatory Effects of Vitamin D in Tumorigenesis
In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium and phosphorus absorption, as well… Expand
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Review
2018
Review
2018
Mutant p53 as a guardian of the cancer cell
Forty years of research have established that the p53 tumor suppressor provides a major barrier to neoplastic transformation and… Expand
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Highly Cited
2009
Highly Cited
2009
Prominin1 marks intestinal stem cells that are susceptible to neoplastic transformation
Cancer stem cells are remarkably similar to normal stem cells: both self-renew, are multipotent and express common surface… Expand
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Highly Cited
2004
Highly Cited
2004
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression.
Many studies have used DNA microarrays to identify the gene expression signatures of human cancer, yet the critical features of… Expand
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Highly Cited
2003
Highly Cited
2003
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
The Polycomb Group Protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to… Expand
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Review
2003
Review
2003
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial… Expand
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