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Neoplastic Cell Transformation

Known as: neoplastic transformation, Cell Transformation, Neoplastic, Cell Neoplastic Transformation 
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Cancer stem cells are remarkably similar to normal stem cells: both self-renew, are multipotent and express common surface… Expand
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Highly Cited
2005
Highly Cited
2005
Cellular senescence has been theorized to oppose neoplastic transformation triggered by activation of oncogenic pathways in vitro… Expand
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Highly Cited
2004
Highly Cited
2004
Many studies have used DNA microarrays to identify the gene expression signatures of human cancer, yet the critical features of… Expand
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Highly Cited
2004
Highly Cited
2004
Recent evidence suggests that human cells require more genetic changes for neoplastic transformation than do their murine… Expand
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Highly Cited
2003
Highly Cited
2003
The Polycomb Group Protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to… Expand
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Review
2003
Review
2003
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial… Expand
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Review
2001
Review
2001
A plethora of physiological and pathological stimuli induce and activate a group of DNA binding proteins that form AP-1 dimers… Expand
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Review
2000
Review
2000
  • P. Polakis
  • Genes & development
  • 2000
  • Corpus ID: 14960846
The regulation of cell growth and survival can be subverted by a variety of genetic defects that alter transcriptional programs… Expand
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Review
1995
Review
1995
Grasping requires coding of the object's intrinsic properties (size and shape), and the transformation of these properties into a… Expand
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Highly Cited
1993
Highly Cited
1993
DEREGULATION of cell proliferation is a hallmark of neoplastic transformation. Alteration in growth control pathways must… Expand