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Neoplastic Cell Transformation

Known as: neoplastic transformation, Cell Transformation, Neoplastic, Cell Neoplastic Transformation 
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities… 
National Institutes of Health

Related topics

Related topics

50 relations
AML1/TEL FUSION GENEANP32C protein, humanANP32C wt AlleleARHGEF5 gene

Broader (1)

metaplastic cell transformation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Generation of a prostate from a single adult stem cell
The existence of prostate stem cells (PSCs) was first postulated from the observation that normal prostate regeneration can occur… 
Highly Cited
2006
Highly Cited
2006
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior.
PURPOSE We investigated the global microRNA expression patterns in normal pancreas, pancreatic endocrine tumors and acinar… 
Review
2003
Review
2003
Role of folate in colon cancer development and progression.
Folate, a water-soluble B vitamin and important cofactor in 1-carbon transfer, is an important nutritional factor that may… 
Highly Cited
1996
Highly Cited
1996
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
Using a new strategy for tumour suppressor gene isolation based on subtractive hybridization and the subsequent selection of… 
Highly Cited
1995
Highly Cited
1995
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas.
In the present study we demonstrate that erbB-3 and erbB-2 cooperate in neoplastic transformation. Under conditions in which… 
Highly Cited
1994
Highly Cited
1994
Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat.
Conjugated linoleic acid (CLA) is a collective term which refers to a mixture of positional and geometric isomers of linoleic… 
Review
1992
Review
1992
Aldehyde dehydrogenases and their role in carcinogenesis.
Aldehydes are highly reactive molecules that may have a variety of effects on biological systems. They can be generated from a… 
Highly Cited
1990
Highly Cited
1990
An amino-terminal c-myc domain required for neoplastic transformation activates transcription
The product of the c-myc proto-oncogene is a nuclear phosphoprotein whose normal cellular function has not yet been defined. c… 
Highly Cited
1982
Highly Cited
1982
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus
A normal human gene homologous to the p21 ras oncogene of Harvey murine sarcoma virus induced oncogenic transformation and high… 
Highly Cited
1978
Highly Cited
1978
Evidence for the progressive nature of neoplastic transformation in vitro.
The temporal acquisition of in vitro phenotypes associated with neoplasia were examined after exposure of Syrian hamster embryo… 
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